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Trip11
Gene Detail
Symbol

Name
ID
Trip11
thyroid hormone receptor interactor 11
MGI:1924393
Synonyms
2610511G22Rik, 3110031G15Rik, 6030460N08Rik, GMAP-210, TRIP230
Feature Type
protein coding gene
Genetic Map
Chromosome 12
51.30 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:101834043-101913267 bp, - strand
From VEGA annotation of GRCm38

  79225 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20897  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: TRIP11
Gene Tree: Trip11

Human
homologs
TRIP11, thyroid hormone receptor interactor 11
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9321
neXtProt AC: NX_Q15643

Human Synonyms: ACG1A, CEV14, GMAP210, GMAP-210, TRIP-11, TRIP230

Human Chr (Location): 14q31-q32; chr14:91965991-92040140 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TRIP11

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Chemically induced (ENU)(1) Gene trapped(11)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null allele exhibit neonatal lethality associated with small size, lung hypoplasia, omphalocele, and ventricular septal defects.
 
Human Diseases Modeled in Mice Using Trip11 (1)    Mutations Annotated to Human Diseases (1)    Phenotype Images(1)
Interactions
Trip11 interacts with 417 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process ventricular septum development
Component acrosomal membrane, cis-Golgi network, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase trip11    NEW 
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000039943 (Evidence)
Ensembl Gene Model ENSMUSG00000021188 (Evidence)
Entrez Gene 109181 (Evidence)
DFCI TC1589622, TC1603459, TC1606641, TC1610883, TC1613673, TC1662986
Consensus CDS Project CCDS49143.1
International Mouse Phenotyping Consortium Status Trip11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000039943 VEGA Gene Model | MGI Sequence Detail 79225 C57BL/6J ±  kb
transcript OTTMUST00000103784 VEGA | MGI Sequence Detail 9873 Not Applicable 
polypeptide OTTMUSP00000058012 VEGA | MGI Sequence Detail 1976 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(8) UniProt(11)
Polymorphisms
SNPs within 2kb(491 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000237 GRIP
InterPro IPR010396 Orthopoxvirus A5
Protein Ontology PR:000016671 thyroid receptor-interacting protein 11
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:217667 May-Simera HL, et al., Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea. Development. 2015 Feb 1;142(3):555-66
All references(35)
Disease annotation references (1)
Other
accession IDs
MGI:1917181, MGI:1920385, MGI:2144830

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory