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Arid2 Gene Detail
Summary
  • Symbol
    Arid2
  • Name
    AT rich interactive domain 2 (ARID, RFX-like)
  • Synonyms
    1700124K17Rik, 4432409D24Rik, zipzap/p200
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924294
    NCBI Gene: 77044
  • Gene Overview
    MyGene.info: ARID2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:96287518-96404992 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 52.37 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    292 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924294
protein coding gene Chr15:96287518-96405463 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022268
protein coding gene Chr15:97861628-97985959 (+)
A/J MGP_AJ_G0022227
protein coding gene Chr15:94034528-94153800 (+)
AKR/J MGP_AKRJ_G0022202
protein coding gene Chr15:96854212-96979321 (+)
BALB/cJ MGP_BALBcJ_G0022233
protein coding gene Chr15:94232102-94350683 (+)
C3H/HeJ MGP_C3HHeJ_G0022003
protein coding gene Chr15:96904208-97031167 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022678
protein coding gene Chr15:101486040-101616947 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020204
protein coding gene Chr15:90027041-90151252 (+)
CAST/EiJ MGP_CASTEiJ_G0021525
protein coding gene Chr15:97769913-97896185 (+)
CBA/J MGP_CBAJ_G0021970
protein coding gene Chr15:104866855-104997621 (+)
DBA/2J MGP_DBA2J_G0022097
protein coding gene Chr15:93478400-93598497 (+)
FVB/NJ MGP_FVBNJ_G0022076
protein coding gene Chr15:92463460-92583430 (+)
LP/J MGP_LPJ_G0022168
protein coding gene Chr15:97983760-98109327 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022096
protein coding gene Chr15:109078753-109206434 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022693
protein coding gene Chr15:96981063-97107835 (+)
PWK/PhJ MGP_PWKPhJ_G0021266
protein coding gene Chr15:93553787-93673228 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021100
protein coding gene Chr15:96778324-96904983 (+)
WSB/EiJ MGP_WSBEiJ_G0021574
protein coding gene Chr15:97487007-97622557 (+)



Homology
more
  • Human Ortholog
    ARID2, AT-rich interaction domain 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARID2, AT-rich interaction domain 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAF200, CSS6, p200
  • Links
    NCBI Gene ID: 196528
    neXtProt AC: NX_Q68CP9
    UniProt: Q68CP9

  • Chr Location
    12q12; chr12:45729683-45908037 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14601
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ARID2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human ARID2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit embryonic lethality between E12.5 and E14.5, congenital heart defects, impaired coronary artery development, subcutaneous edema and hemorrhage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033237 Ensembl Gene Model | MGI Sequence Detail 117475 C57BL/6J ±  kb
    transcript ENSMUST00000096250 Ensembl | MGI Sequence Detail 8507 Not Applicable  
    polypeptide ENSMUSP00000093969 Ensembl | MGI Sequence Detail 1828 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 204
      cDNA 203
      Primer pair 1

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1920892
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 8
      Diseases 1
      Gene Ontology 6
      Phenotypes 30
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:264370 Sima J, et al., Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory