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Cecr2
Gene Detail
 Symbol
Name
ID
Cecr2
cat eye syndrome chromosome region, candidate 2
MGI:1923799
Synonyms 2610101O16Rik, 2810409N01Rik, Gtl4, mKIAA1740
Feature Type protein coding gene
Genetic Map
Chromosome 6
56.97 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:120666369-120771190 bp, + strand
From VEGA annotation of GRCm38

  104822 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:64662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Cecr2

Human
homologs
Human Homolog CECR2, cat eye syndrome chromosome region, candidate 2
NCBI Gene ID 27443
neXtProt AC  NX_Q9BXF3
Human Chr (Location)  22q11.2; chr22:17369730-17558147 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(56) : Gene trapped(53) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice display varied penetrance of exencephaly depending on genetic background.
 
Human Diseases Modeled Using Mouse Cecr2 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Cecr2 interacts with 460 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process ATP-dependent chromatin remodeling, cochlea development, ...
Component CERF complex, ISWI-type complex, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (6)    Tissues (1)    Images (6)
Theiler Stages: 23
Assay TypeResults
RNA in situ 6
cDNA source data(88)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(89) Genomic(1) cDNA(88)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023741 (Evidence)
Ensembl Gene ModelENSMUSG00000071226 (Evidence)
Entrez Gene330409 (Evidence)
UniGene333357
DFCITC1582410, TC1598244, TC1600810, TC1618227
DoTSDT.40134553, DT.55203056, DT.91592660, DT.97353260
NIA Mouse Gene IndexU007344
Consensus CDS ProjectCCDS51890.1
International Mouse Knockout Project StatusCecr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023741 VEGA Gene Model | MGI Sequence Detail 104822 C57BL/6J ±  kb
transcript OTTMUST00000057984 VEGA | MGI Sequence Detail 4849 Not Applicable 
polypeptide OTTMUSP00000028044 VEGA | MGI Sequence Detail 1453 Not Applicable 

For the selected sequences
All sequences(83) RefSeq(26) UniProt(7)
Polymorphisms SNPs within 2kb(424 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
Protein Ontology PR:000005314 cat eye syndrome critical region protein 2
References (Earliest) J:50092 Tate P, et al., Capturing novel mouse genes encoding chromosomal and other nuclear proteins. J Cell Sci. 1998 Sep;111(Pt 17):2575-85
(Latest) J:197015 Thompson PJ, et al., CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis. J Mol Biol. 2012 Feb 3;415(5):793-806
All references(43)
Disease annotation references (1)
Other
accession IDs
MGI:1309479, MGI:1913831

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory