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Cecr2
Gene Detail
Symbol

Name
ID
Cecr2
cat eye syndrome chromosome region, candidate 2
MGI:1923799
Synonyms
2610101O16Rik, 2810409N01Rik, Gtl4, mKIAA1740
Feature Type
protein coding gene
Genetic Map
Chromosome 6
56.97 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:120666369-120771190 bp, + strand
From VEGA annotation of GRCm38

  104822 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:64662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: CECR2
Gene Tree: Cecr2

Human
homologs
CECR2, cat eye syndrome chromosome region, candidate 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 27443
neXtProt AC: NX_Q9BXF3

Human Chr (Location): 22q11.2; chr22:17359949-17558155 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(57) : Gene trapped(53) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice display varied penetrance of exencephaly depending on genetic background.
 
Human Diseases Modeled in Mice Using Cecr2 (1)    Mutations Annotated to Human Diseases (1)   
Interactions
Cecr2 interacts with 459 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process ATP-dependent chromatin remodeling, cochlea development, ...
Component CERF complex, ISWI-type complex, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (6)    Tissues (1)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 6
cDNA source data(88)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA CECR2 ; Xenbase cecr2    NEW 
Molecular
reagents
All nucleic(89) Genomic(1) cDNA(88)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000023741 (Evidence)
Ensembl Gene Model ENSMUSG00000071226 (Evidence)
Entrez Gene 330409 (Evidence)
UniGene 333357
DFCI TC1582410, TC1598244, TC1600810, TC1618227
DoTS DT.40134553, DT.55203056, DT.91592660, DT.97353260
NIA Mouse Gene Index U007344
Consensus CDS Project CCDS51890.1
International Mouse Phenotyping Consortium Status Cecr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023741 VEGA Gene Model | MGI Sequence Detail 104822 C57BL/6J ±  kb
transcript OTTMUST00000057984 VEGA | MGI Sequence Detail 4849 Not Applicable 
polypeptide OTTMUSP00000028044 VEGA | MGI Sequence Detail 1453 Not Applicable 

For the selected sequences
All sequences(75) RefSeq(18) UniProt(7)
Polymorphisms
SNPs within 2kb(424 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
InterPro IPR029614 Cat eye syndrome critical region protein 2
Protein Ontology PR:000005314 cat eye syndrome critical region protein 2
References
(Earliest) J:50092 Tate P, et al., Capturing novel mouse genes encoding chromosomal and other nuclear proteins. J Cell Sci. 1998 Sep;111(Pt 17):2575-85
(Latest) J:197015 Thompson PJ, et al., CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis. J Mol Biol. 2012 Feb 3;415(5):793-806
All references(43)
Disease annotation references (1)
Other
accession IDs
MGI:1309479, MGI:1913831

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory