Phenotypes Associated with This Genotype

Genotype
MGI:3574274

• Allelic Composition: Cecr2^{Gt(pGT1)1Hemc}/Cecr2^{Gt(pGT1)1Hemc}
• Genetic Background: involves: 129P2/OlaHsd * BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:96325 )

• most homozygous mutants die perinatally, however 7.5% of homozgygotes are found at weaning and these are indistinguishable from wildtype

vision/eye

absent eyelids ( J:96325 )

• some homozygous mutants lacked eyelids

nervous system

exencephaly ( J:96325 )

• neural tube defect exencephaly was observed at a frequency of 67% in homozygotes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
anencephaly		DOID:0060668	OMIM:206500	J:96325