About   Help   FAQ
Trafd1
Gene Detail
Symbol

Name
ID
Trafd1
TRAF type zinc finger domain containing 1
MGI:1923551
Synonyms
1110008K06Rik, Fln29
Feature Type
protein coding gene
Genetic Map
Chromosome 5
61.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:121371725-121385632 bp, - strand
From VEGA annotation of GRCm38

  13908 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31399  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Trafd1

Human
homologs
Human Homolog TRAFD1, TRAF-type zinc finger domain containing 1
NCBI Gene ID 10906
neXtProt AC  NX_O14545
Human Synonyms  FLN29
Human Chr (Location)  12q; chr12:112125545-112153604 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit increased susceptibility to endotoxin shock and decreased susceptibility to viral infection.
 
Interactions
Trafd1 interacts with 90 markers (Mir22, Mir25, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process negative regulation of innate immune response
Component cellular_component
Function metal ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (12)    Tissues (7)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
cDNA source data(115)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(116) cDNA(116)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026315 (Evidence)
Ensembl Gene ModelENSMUSG00000042726 (Evidence)
Entrez Gene231712 (Evidence)
UniGene20488
DFCITC1601555, TC1574137, TC1645475, TC1602921, TC1677599
DoTSDT.101713340, DT.101258317, DT.110683329, DT.55200141, DT.99862332, DT.94293015
NIA Mouse Gene IndexU026680
Consensus CDS ProjectCCDS51638.1, CCDS51639.1
International Mouse Knockout Project StatusTrafd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026315 VEGA Gene Model | MGI Sequence Detail 13908 C57BL/6J ±  kb
transcript OTTMUST00000065083 VEGA | MGI Sequence Detail 2503 Not Applicable 
polypeptide OTTMUSP00000032388 VEGA | MGI Sequence Detail 580 Not Applicable 

For the selected sequences
All sequences(79) RefSeq(12) UniProt(7)
Polymorphisms
SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR001293 Zinc finger, TRAF-type
Protein Ontology PR:000016605 TRAF-type zinc finger domain-containing protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory