Trafd1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trafd1
TRAF type zinc finger domain containing 1
MGI:1923551

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trafd1^{tm1a(EUCOMM)Wtsi}/Trafd1^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Trafd1^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body weight	J:165965
	decreased total body fat amount	J:165965
Trafd1^tm1Ayos/Trafd1^tm1Ayos involves: 129 * C57BL/6J	decreased susceptibility to Riboviria infection	J:144594
	increased circulating alanine transaminase level	J:144594
	increased circulating interleukin-6 level	J:144594
	increased interleukin-6 secretion	J:144594
	increased interleukin-12 secretion	J:144594
	increased susceptibility to endotoxin shock	J:144594
	increased susceptibility to induced morbidity/mortality	J:144594
	increased tumor necrosis factor secretion	J:144594

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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