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Erp44
Gene Detail
 Symbol
Name
ID
Erp44
endoplasmic reticulum protein 44
MGI:1923549
Synonyms 1110001E24Rik, Txndc4
Feature Type protein coding gene
Genetic Map
Chromosome 4
26.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:48193323-48279558 bp, - strand
From VEGA annotation of GRCm38

  86236 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12638  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: protein disulfide-isomerase
Gene Tree: Erp44

Human
homologs
Human Homolog ERP44, endoplasmic reticulum protein 44
NCBI Gene ID 23071
neXtProt AC  NX_Q9BS26
Human Synonyms  PDIA10, TXNDC4
Human Chr (Location)  9q31.1; chr9:99979179-100099048 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Chemically induced (ENU)(1) Gene trapped(13) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced allele exhibit light coat colour, small stature and scaly tail.
 
Interactions
Erp44 interacts with 217 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cell redox homeostasis, glycoprotein metabolic process, ...
Component cell surface, endoplasmic reticulum, ...
Function protein binding, protein disulfide isomerase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (40)    Tissues (6)    Images (18)
Theiler Stages: 23
Assay TypeResults
RNA in situ 40
cDNA source data(149)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(149) cDNA(149)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000006817 (Evidence)
Ensembl Gene ModelENSMUSG00000028343 (Evidence)
Entrez Gene76299 (Evidence)
UniGene317701
DFCITC1575650, TC1662792
DoTSDT.493480
NIA Mouse Gene IndexU025046
Consensus CDS ProjectCCDS18165.1
International Mouse Knockout Project StatusErp44
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006817 VEGA Gene Model | MGI Sequence Detail 86236 C57BL/6J ±  kb
transcript OTTMUST00000015705 VEGA | MGI Sequence Detail 2624 Not Applicable 
polypeptide OTTMUSP00000007220 VEGA | MGI Sequence Detail 406 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(466 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013766 Thioredoxin domain
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000016862 endoplasmic reticulum resident protein 44
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203503 Wei Z, et al., C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis. J Biol Chem. 2013 Apr 12;288(15):10214-29
All references(45)
Other
accession IDs
MGI:2140383, MGI:2140418

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory