Erp44 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Erp44
endoplasmic reticulum protein 44
MGI:1923549

33 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Erp44^Gt(XB599)Byg/Erp44⁺ B6.129P2(129S)-Erp44^Gt(XB599)Byg	abnormal calcium ion homeostasis	J:244948
	abnormal fetal cardiomyocyte physiology	J:244948
	abnormal mitochondrial crista morphology	J:244948
	abnormal mitochondrial matrix morphology	J:244948
	abnormal mitochondrial physiology	J:244948
	abnormal myocardial fiber mitochondrial morphology	J:244948
	abnormal susceptibility to injury induced morbidity/mortality	J:244948
	dilated mitochondrion	J:244948
	increased endoplasmic reticulum stress	J:244948
	increased myocardial fiber apoptosis	J:244948
	increased response of heart to induced stress	J:244948
	myocardial fiber disarray	J:244948
	oxidative stress	J:244948
	premature death	J:244948
Erp44^Gt(XB599)Byg/Erp44^Gt(XB599)Byg B6.129P2(129S)-Erp44^Gt(XB599)Byg	abnormal calcium ion homeostasis	J:244948
	abnormal fetal cardiomyocyte physiology	J:244948
	abnormal heart echocardiography feature	J:244948
	abnormal heart morphology	J:244948
	abnormal mitochondrial physiology	J:244948
	abnormal myocardial fiber mitochondrial morphology	J:244948
	cardiac fibrosis	J:244948
	cardiac hypertrophy	J:244948
	decreased body size	J:244948
	decreased body weight	J:244948
	decreased heart left ventricle muscle contractility	J:244948
	embryonic lethality during organogenesis, incomplete penetrance	J:244948
	encephalomeningocele	J:244948
	increased cardiomyocyte apoptosis	J:244948
	increased endoplasmic reticulum stress	J:244948
	increased heart weight	J:244948
	increased mitochondrial size	J:244948
	increased myocardial fiber size	J:244948
	myocardial fiber disarray	J:244948
	oxidative stress	J:244948
	premature death	J:244948
	preweaning lethality, incomplete penetrance	J:244948
Erp44^m1Anu/Erp44^m1Anu involves: C57BL/6JSfdAnu * CBA/H	abnormal coat/hair pigmentation	J:104190
	decreased body height	J:104190
	scaly skin	J:104190
Erp44^{tm1a(KOMP)Wtsi}/Erp44⁺ C57BL/6N-Erp44^{tm1a(KOMP)Wtsi}/Wtsi	increased bone mineral content	J:211773
	increased lean body mass	J:211773
Erp44^{tm1a(KOMP)Wtsi}/Erp44^{tm1a(KOMP)Wtsi} C57BL/6N-Erp44^{tm1a(KOMP)Wtsi}/Wtsi	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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