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Cant1 Gene Detail
Summary
  • Symbol
    Cant1
  • Name
    calcium activated nucleotidase 1
  • Synonyms
    5830420C20Rik, Apy1h, D11Bwg0554e, SCAN-1, Shapy
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923275
    NCBI Gene: 76025
  • Gene Overview
    MyGene.info: CANT1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:118406289-118419086 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 83.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923275
protein coding gene Chr11:118406289-118419134 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019467
protein coding gene Chr11:122729798-122742731 (-)
A/J MGP_AJ_G0019435
protein coding gene Chr11:117292864-117305841 (-)
AKR/J MGP_AKRJ_G0019405
protein coding gene Chr11:120847967-120860885 (-)
BALB/cJ MGP_BALBcJ_G0019410
protein coding gene Chr11:117654618-117667407 (-)
C3H/HeJ MGP_C3HHeJ_G0019216
protein coding gene Chr11:121157120-121170040 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019859
protein coding gene Chr11:126491977-126504766 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017484
protein coding gene Chr11:114292334-114305146 (-)
CAST/EiJ MGP_CASTEiJ_G0018770
protein coding gene Chr11:122579105-122592031 (-)
CBA/J MGP_CBAJ_G0019187
protein coding gene Chr11:131406009-131418923 (-)
DBA/2J MGP_DBA2J_G0019299
protein coding gene Chr11:116674080-116687006 (-)
FVB/NJ MGP_FVBNJ_G0019291
protein coding gene Chr11:116320617-116333537 (-)
LP/J MGP_LPJ_G0019369
protein coding gene Chr11:123044826-123057742 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019324
protein coding gene Chr11:130397562-130410484 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019898
protein coding gene Chr11:121515325-121528250 (-)
PWK/PhJ MGP_PWKPhJ_G0018536
protein coding gene Chr11:118059511-118072448 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018328
protein coding gene Chr11:121233509-121246421 (-)
WSB/EiJ MGP_WSBEiJ_G0018822
protein coding gene Chr11:121463948-121477658 (-)



Homology
more
  • Human Ortholog
    CANT1, calcium activated nucleotidase 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CANT1, calcium activated nucleotidase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DBQD, DBQD1, EDM7, SCAN1, SCAN-1, SHAPY
  • Links
    NCBI Gene ID: 124583
    neXtProt AC: NX_Q8WVQ1
    UniProt: Q8WVQ1

  • Chr Location
    17q25.3; chr17:78991716-79009817 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human CANT1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025575 Ensembl Gene Model | MGI Sequence Detail 12798 C57BL/6J ±  kb
    transcript ENSMUST00000106289 Ensembl | MGI Sequence Detail 1600 Not Applicable  
    polypeptide ENSMUSP00000101896 Ensembl | MGI Sequence Detail 440 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 65
      cDNA 64
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-34060, MGI:106367, MGI:1338006
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 8
    • Earliest
      J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory