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Cant1
Gene Detail
 Symbol
Name
ID
Cant1
calcium activated nucleotidase 1
MGI:1923275
Synonyms 5830420C20Rik, Apy1h, D11Bwg0554e, SCAN-1, Shapy
Feature Type protein coding gene
Genetic Map
Chromosome 11
83.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:118406289-118419086 bp, - strand
From VEGA annotation of GRCm38

  12798 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69460  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 zebrafish

Gene Tree: Cant1

Human
homologs
Human Homolog CANT1, calcium activated nucleotidase 1
NCBI Gene ID 124583
neXtProt AC  NX_Q8WVQ1
Human Synonyms  DBQD, SCAN1, SCAN-1, SHAPY
Human Chr (Location)  17q25.3; chr17:78991716-79009817 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CANT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cant1 interacts with 172 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process positive regulation of I-kappaB kinase/NF-kappaB signaling, proteoglycan biosynthetic process, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function calcium ion binding, guanosine-diphosphatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (119)    Tissues (96)    Images (30)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 119
cDNA source data(63)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(64) cDNA(63) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000003887 (Evidence)
Ensembl Gene ModelENSMUSG00000025575 (Evidence)
Entrez Gene76025 (Evidence)
UniGene177551
DFCITC1576022, TC1595190, TC1596145, TC1682844
DoTSDT.101739594, DT.110541144, DT.529239, DT.530976, DT.91340055, DT.91368961, DT.97358224
NIA Mouse Gene IndexU033684
EC3.6.1.6
Consensus CDS ProjectCCDS25702.1, CCDS59572.1
International Mouse Knockout Project StatusCant1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003887 VEGA Gene Model | MGI Sequence Detail 12798 C57BL/6J ±  kb
transcript OTTMUST00000008823 VEGA | MGI Sequence Detail 1600 Not Applicable 
polypeptide OTTMUSP00000004298 VEGA | MGI Sequence Detail 440 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(26) UniProt(1)
Polymorphisms SNPs within 2kb(79 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009283 Apyrase
Protein Ontology PR:000005004 soluble calcium-activated nucleotidase 1
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(40)
Other
accession IDs
MGD-MRK-34060, MGI:106367, MGI:1338006

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory