Rnf139
Gene Detail

Symbol Name ID

Rnf139 ring finger protein 139 MGI:1923091

Synonyms

4930555P18Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 15

25.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr15:58889229-58902390 bp, + strand From NCBI annotation of GRCm38   13162 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5222  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rnf139

Human homologs

Human Homolog		RNF139, ring finger protein 139
NCBI Gene ID		11236
neXtProt AC		NX_Q8WU17
Human Synonyms		HRCA1, RCA1, TRC8
Human Chr (Location)		8q24; chr8:125487008-125500859 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RNF139

Alleles and phenotypes

All alleles(2) : Targeted(1) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	negative regulation of cell proliferation, negative regulation of translation, ...
Component	endoplasmic reticulum, integral to membrane, ...
Function	ligase activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (29)    Images (4)
Theiler Stages: 17, 18, 21, 23

Assay Type	Results
RNA in situ	29

cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(7)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000037075 (Evidence)
Entrez Gene	75841 (Evidence)
DFCI	TC1576740, TC1623250, TC1642831, TC1681742
NIA Mouse Gene Index	U016270
EC	6.3.2.-
Consensus CDS Project	CCDS27494.1
International Mouse Knockout Project Status	Rnf139

Sequences

Length	Strain/Species
genomic	75841	NCBI Gene Model | MGI Sequence Detail	13162	C57BL/6J
transcript	NM_175226	RefSeq | MGI Sequence Detail	4348	C57BL/6
polypeptide	Q7TMV1	UniProt | EBI | MGI Sequence Detail	668	Not Applicable

All sequences(21) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(21 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR025754	TRC8 N-terminal domain
InterPro	IPR013083	Zinc finger, RING/FYVE/PHD-type
InterPro	IPR001841	Zinc finger, RING-type
Protein Ontology	PR:000014085	E3 ubiquitin-protein ligase RNF139

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)