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Rnf139
Gene Detail
 Symbol
Name
ID
Rnf139
ring finger protein 139
MGI:1923091
Synonyms 4930555P18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 15
25.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:58889229-58902390 bp, + strand
From NCBI annotation of GRCm38

  13162 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5222  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rnf139

Human
homologs
Human Homolog RNF139, ring finger protein 139
NCBI Gene ID 11236
neXtProt AC  NX_Q8WU17
Human Synonyms  HRCA1, RCA1, TRC8
Human Chr (Location)  8q24; chr8:124474767-124488618 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RNF139
Alleles
and
phenotypes
All alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process negative regulation of cell proliferation, negative regulation of translation, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (29)    Images (4)
Theiler Stages: 17, 18, 21, 23
Assay TypeResults
RNA in situ 29
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000037075 (Evidence)
Entrez Gene75841 (Evidence)
DFCITC1576740, TC1623250, TC1642831, TC1681742
NIA Mouse Gene IndexU016270
EC6.3.2.-
Consensus CDS ProjectCCDS27494.1
International Mouse Knockout Project StatusRnf139
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 75841 NCBI Gene Model | MGI Sequence Detail 13162 C57BL/6J ±  kb
transcript NM_175226 RefSeq | MGI Sequence Detail 4348 C57BL/6 
polypeptide Q7TMV1 UniProt | EBI | MGI Sequence Detail 668 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025754 TRC8 N-terminal domain
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000014085 E3 ubiquitin-protein ligase RNF139
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory