About   Help   FAQ
Rnf139 Gene Detail
Summary
  • Symbol
    Rnf139
  • Name
    ring finger protein 139
  • Synonyms
    4930555P18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923091
    NCBI Gene: 75841
  • Gene Overview
    MyGene.info: RNF139
Location & Maps
more
  • Sequence Map
    Chr15:58889229-58902390 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13162 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RNF139, ring finger protein 139
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RNF139, ring finger protein 139
    Orthology source: HomoloGene
  • Synonyms
    HRCA1, RCA1, TRC8
  • Links
    NCBI Gene ID: 11236
    neXtProt AC: NX_Q8WU17

  • Chr Location
    8q24; chr8:124474767-124488618 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5222
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: RNF139
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human RNF139 associations

Human Disease Mouse Models
       Renal Cell Carcinoma, Nonpapillary; RCC   OMIM: 144700
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    3
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Rnf139
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75841 NCBI Gene Model | MGI Sequence Detail 13162 C57BL/6J ±  kb
transcript NM_175226 RefSeq | MGI Sequence Detail 4348 C57BL/6  
polypeptide Q7TMV1 UniProt | EBI | MGI Sequence Detail 668 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    32 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 25
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/19/2016
MGI 6.03
The Jackson Laboratory