Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable protease binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein destabilization; and regulation of protein metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex. Predicted to be active in endomembrane system. Is expressed in bladder; central nervous system; testis; and ureter. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human RNF139 (ring finger protein 139).