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Capsl Gene Detail
Summary
  • Symbol
    Capsl
  • Name
    calcyphosine-like
  • Synonyms
    1700028N11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922818
    NCBI Gene: 75568
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:9436136-9466125 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 4.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    693 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922818
 protein coding gene Chr15:9436114-9466125 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021715
 protein coding gene Chr15:6530533-6559575 (+)
A/J MGP_AJ_G0021675
 protein coding gene Chr15:6354636-6381450 (+)
AKR/J MGP_AKRJ_G0021653
 protein coding gene Chr15:6519963-6543708 (+)
BALB/cJ MGP_BALBcJ_G0021682
 protein coding gene Chr15:6264611-6293134 (+)
C3H/HeJ MGP_C3HHeJ_G0021458
 protein coding gene Chr15:6454105-6477776 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022121
 protein coding gene Chr15:6771303-6797060 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019658
 protein coding gene Chr15:5874251-5898997 (+)
CAST/EiJ MGP_CASTEiJ_G0020974
 protein coding gene Chr15:6519123-6543965 (+)
CBA/J MGP_CBAJ_G0021427
 protein coding gene Chr15:6924785-6951124 (+)
DBA/2J MGP_DBA2J_G0021551
 protein coding gene Chr15:6241948-6265992 (+)
FVB/NJ MGP_FVBNJ_G0021529
 protein coding gene Chr15:6133735-6157734 (+)
LP/J MGP_LPJ_G0021619
 protein coding gene Chr15:6451843-6476352 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021554
 protein coding gene Chr15:7144412-7168449 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022144
 protein coding gene Chr15:6489505-6515169 (+)
PWK/PhJ MGP_PWKPhJ_G0020717
 protein coding gene Chr15:6371608-6395589 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020555
 protein coding gene Chr15:6440559-6464729 (+)
WSB/EiJ MGP_WSBEiJ_G0021030
 protein coding gene Chr15:6500006-6523511 (+)



Homology
more
  • Human Ortholog
    CAPSL, calcyphosine like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAPSL, calcyphosine like
  • Links
    NCBI Gene ID: 133690
    UniProt: Q8WWF8

  • Chr Location
    5p13.2; chr5:35904288-35938779 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Capsl mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Vascular endothelial cell-specific inactivation recapitulates familial exudative vitreoretinopathy-like retinal vascular defects, with delayed radial/vertical vascular progression and compromised endothelial proliferation/migration in the retina.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    778
  • Tissues
    15
  • cDNA Data
    9
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75568 NCBI Gene Model | MGI Sequence Detail 29990 C57BL/6J ±  kb
    transcript NM_029341 RefSeq | MGI Sequence Detail 928 C57BL/6  
    polypeptide Q6P8Y1 UniProt | EBI | MGI Sequence Detail 208 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2146200
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
    • Latest
      J:365043 Liu W, et al., Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy. Elife. 2024 Sep 12;13
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/07/2025
    MGI 6.24     		The Jackson Laboratory