Capsl^em1Xjz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Capsl^em1Xjz
• Name: calcyphosine-like; endonuclease-mediated mutation 1, Xianjun Zhu
• MGI ID: MGI:8190488
• Synonyms: Capsl^em1Zxj, Capsl^loxP
• Gene: Capsl Location: Chr15:9436136-9466125 bp, + strand Genetic Position: Chr15, 4.09 cM
• Alliance: Capsl^em1Xjz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology generated a floxed conditional allele. (J:365043)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Capsl Mutation: 23 strains or lines available

References

• Original: J:365043 Liu W, et al., Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy. Elife. 2024 Sep 12;13
• All: 1 reference(s)