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Nme5
Gene Detail
 Symbol
Name
ID
Nme5
NME/NM23 family member 5
MGI:1922783
Synonyms 1700019D05Rik, Nm23-M5, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
Feature Type protein coding gene
Genetic Map
Chromosome 18
18.69 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:34562634-34579115 bp, - strand
From VEGA annotation of GRCm38

  16482 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2628  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: nucleoside-diphosphate kinase homolog with Dpy-30 motif (NDK-H5)
Gene Tree: Nme5

Human
homologs
Human Homolog NME5, NME/NM23 family member 5
NCBI Gene ID 8382
neXtProt AC  NX_P56597
Human Synonyms  NM23H5, NM23-H5, RSPH23
Human Chr (Location)  5q31; chr5:138115172-138139443 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mice exhibit hydrocephaly and male spermatogenesis defects.
 
Interactions
Nme5 interacts with 43 markers (Mir30b, Mir34a, Mir101a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell differentiation, cilium assembly, ...
Component sperm flagellum
Function ATP binding, nucleoside diphosphate kinase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000033174 (Evidence)
Ensembl Gene ModelENSMUSG00000035984 (Evidence)
Entrez Gene75533 (Evidence)
UniGene275430
DFCITC1586114, TC1647606
DoTSDT.101368808, DT.91338673, DT.94288401
NIA Mouse Gene IndexU038307
Consensus CDS ProjectCCDS29130.1
International Mouse Knockout Project StatusNme5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033174 VEGA Gene Model | MGI Sequence Detail 16482 C57BL/6J ±  kb
transcript OTTMUST00000082987 VEGA | MGI Sequence Detail 843 Not Applicable 
polypeptide OTTMUSP00000044531 VEGA | MGI Sequence Detail 211 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(5) UniProt(3)
Polymorphisms SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007858 Dpy-30 motif
InterPro IPR001564 Nucleoside diphosphate kinase
InterPro IPR012410 Nucleoside-diphosphate kinase-like NDK-H5
Protein Ontology PR:000011285 nucleoside diphosphate kinase homolog 5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory