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Kif27
Gene Detail
 Symbol
Name
ID
Kif27
kinesin family member 27
MGI:1922300
Synonyms 4930517I18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 13
30.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:58287516-58354862 bp, - strand
From NCBI annotation of GRCm38

  67347 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69235  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Kif27

Human
homologs
Human Homolog KIF27, kinesin family member 27
NCBI Gene ID 55582
neXtProt AC  NX_Q86VH2
Human Chr (Location)  9q21.32; chr9:83836698-83921509 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mice are small and die by 8 weeks and exhibit hydrocephalus, rhinitis and otitis media.
 
Interactions
Kif27 interacts with 98 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process ATP catabolic process, cell projection organization, ...
Component cell projection, cilium, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (18)    Images (20)
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RNA in situ 40
Northern blot 12
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000060176 (Evidence)
Entrez Gene75050 (Evidence)
UniGene446094
DFCITC1589387, TC1605514
DoTSDT.101703717
NIA Mouse Gene IndexU034847
Consensus CDS ProjectCCDS26570.1
International Mouse Knockout Project StatusKif27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 75050 NCBI Gene Model | MGI Sequence Detail 67347 C57BL/6J ±  kb
transcript NM_175214 RefSeq | MGI Sequence Detail 4462 Not Specified 
polypeptide Q7M6Z4 UniProt | EBI | MGI Sequence Detail 1394 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(34) UniProt(1)
Polymorphisms SNPs within 2kb(508 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001752 Kinesin, motor domain
InterPro IPR019821 Kinesin, motor region, conserved site
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000009307 kinesin-like protein KIF27
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory