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Kif27
Gene Detail
Symbol

Name
ID
Kif27
kinesin family member 27
MGI:1922300
Synonyms
4930517I18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
30.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:58287516-58354862 bp, - strand
From Ensembl annotation of GRCm38

  67347 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69235  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: KIF27
Gene Tree: Kif27

Human
homologs
KIF27, kinesin family member 27
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55582
neXtProt AC: NX_Q86VH2

Human Chr (Location): 9q21.32; chr9:83836698-83921467 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mice are small and die by 8 weeks and exhibit hydrocephalus, rhinitis and otitis media.
 
Interactions
Kif27 interacts with 98 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cell projection organization, cilium assembly, ...
Component cell projection, cilium, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (18)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 40
Northern blot 12
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase kif27    NEW 
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000060176 (Evidence)
Entrez Gene 75050 (Evidence)
UniGene 446094
DFCI TC1589387, TC1605514
DoTS DT.101703717
NIA Mouse Gene Index U034847
Consensus CDS Project CCDS26570.1
International Mouse Phenotyping Consortium Status Kif27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060176 Ensembl Gene Model | MGI Sequence Detail 67347 C57BL/6J ±  kb
transcript ENSMUST00000043605 Ensembl | MGI Sequence Detail 4462 Not Applicable 
polypeptide ENSMUSP00000043304 Ensembl | MGI Sequence Detail 1394 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(39) UniProt(1)
Polymorphisms
SNPs within 2kb(508 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027640 Kinesin-like protein
InterPro IPR001752 Kinesin motor domain
InterPro IPR019821 Kinesin motor domain, conserved site
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000009307 kinesin-like protein KIF27
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory