Kif27
Gene Detail

Symbol Name ID

Kif27 kinesin family member 27 MGI:1922300

Synonyms

4930517I18Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 13

30.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr13:58287516-58354862 bp, - strand From NCBI annotation of GRCm38   67347 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:69235  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Kif27

Human homologs

Human Homolog		KIF27, kinesin family member 27
NCBI Gene ID		55582
neXtProt AC		NX_Q86VH2
Human Chr (Location)		9q21.32; chr9:86451613-86536342 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(9) : Targeted(2) Gene trapped(7)
 

Homozygous mice are small and die by 8 weeks and exhibit hydrocephalus, rhinitis and otitis media.

 

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	cell projection organization, cilium assembly, ...
Component	cell projection, cilium, ...
Function	ATP binding, microtubule binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (18)    Images (20)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
RNA in situ	40
Northern blot	12

cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000060176 (Evidence)
Entrez Gene	75050 (Evidence)
UniGene	446094
DFCI	TC1589387, TC1605514
DoTS	DT.101703717
NIA Mouse Gene Index	U034847
Consensus CDS Project	CCDS26570.1
International Mouse Knockout Project Status	Kif27

Sequences

Length	Strain/Species
genomic	75050	NCBI Gene Model | MGI Sequence Detail	67347	C57BL/6J
transcript	NM_175214	RefSeq | MGI Sequence Detail	4462	Not Specified
polypeptide	Q7M6Z4	UniProt | EBI | MGI Sequence Detail	1394	Not Applicable

All sequences(15) RefSeq(2) UniProt(1)

Polymorphisms

SNPs within 2kb(508 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR001752	Kinesin, motor domain
InterPro	IPR019821	Kinesin, motor region, conserved site
InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Protein Ontology	PR:000009307	kinesin-like protein KIF27

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(28)