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Tmem106a Gene Detail
Summary
  • Symbol
    Tmem106a
  • Name
    transmembrane protein 106A
  • Synonyms
    0610008L10Rik, MGC:30290, MGC:37887
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922056
    NCBI Gene: 217203
  • Gene Overview
    MyGene.info: TMEM106A
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101582242-101591788 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 65.44 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922056
protein coding gene Chr11:101582242-101591788 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019208
protein coding gene Chr11:104466809-104477573 (+)
A/J MGP_AJ_G0019176
protein coding gene Chr11:100067213-100076764 (+)
AKR/J MGP_AKRJ_G0019145
protein coding gene Chr11:103176392-103187410 (+)
BALB/cJ MGP_BALBcJ_G0019150
protein coding gene Chr11:100558124-100567553 (+)
C3H/HeJ MGP_C3HHeJ_G0018959
protein coding gene Chr11:103352114-103362084 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019599
protein coding gene Chr11:107738562-107749699 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017225
protein coding gene Chr11:97462187-97470026 (+)
CAST/EiJ MGP_CASTEiJ_G0018513
protein coding gene Chr11:104330907-104346671 (+)
CBA/J MGP_CBAJ_G0018928
protein coding gene Chr11:112168155-112179607 (+)
DBA/2J MGP_DBA2J_G0019040
protein coding gene Chr11:99587532-99596830 (+)
FVB/NJ MGP_FVBNJ_G0019030
protein coding gene Chr11:99129798-99142190 (+)
LP/J MGP_LPJ_G0019109
protein coding gene Chr11:104995331-105007342 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019061
protein coding gene Chr11:111733204-111742729 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019637
protein coding gene Chr11:103511632-103521816 (+)
PWK/PhJ MGP_PWKPhJ_G0018276
protein coding gene Chr11:100650985-100661550 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018068
protein coding gene Chr11:103241285-103251633 (+)
WSB/EiJ MGP_WSBEiJ_G0018562
protein coding gene Chr11:103502181-103516191 (+)



Homology
more
  • Human Ortholog
    TMEM106A, transmembrane protein 106A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TMEM106A, transmembrane protein 106A
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 113277
    neXtProt AC: NX_Q96A25
    UniProt: Q96A25

  • Chr Location
    17q21.31; chr17:43211827-43220041 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217203 NCBI Gene Model | MGI Sequence Detail 9547 C57BL/6J ±  kb
transcript NM_001359325 RefSeq | MGI Sequence Detail 2544 C57BL/6  
polypeptide Q8VC04 UniProt | EBI | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144065, MGI:2384951
References
more
  • Summaries
    All 35
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:233118 Abdallah BM, et al., DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. J Bone Miner Res. 2011 Jul;26(7):1457-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory