Tmem106a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem106a
transmembrane protein 106A
MGI:1922056

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmem106a^em1(IMPC)Bay/Tmem106a^em1(IMPC)Bay C57BL/6N-Tmem106a^em1(IMPC)Bay/Bay	abnormal vocalization	J:211773
Tmem106a^em1Cheyy/Tmem106a^em1Cheyy B6.Cg-Tmem106a^em1Cheyy	abnormal macrophage activation involved in immune response	J:345342
	abnormal susceptibility to injury induced morbidity/mortality	J:345342
	normal immune system phenotype	J:345342
	increased circulating interferon-beta level	J:345342
	increased circulating interleukin-6 level	J:345342
	increased circulating tumor necrosis factor level	J:345342
	increased interleukin-6 secretion	J:345342
	increased susceptibility to endotoxin shock	J:345342
	increased susceptibility to induced morbidity/mortality	J:345342
	increased susceptibility to injury	J:345342
	increased tumor necrosis factor secretion	J:345342

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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