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Plpp6 Gene Detail
Summary
  • Symbol
    Plpp6
  • Name
    phospholipid phosphatase 6
  • Synonyms
    4932443D16Rik, Ppapdc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921661
    NCBI Gene: 74411
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:28963953-28966811 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 23.61 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921661
protein coding gene Chr19:28963920-28966811 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025014
protein coding gene Chr19:27393052-27395909 (+)
A/J MGP_AJ_G0024991
protein coding gene Chr19:26008672-26011532 (+)
AKR/J MGP_AKRJ_G0024959
protein coding gene Chr19:26955045-26957902 (+)
BALB/cJ MGP_BALBcJ_G0024990
protein coding gene Chr19:26055427-26058285 (+)
C3H/HeJ MGP_C3HHeJ_G0024746
protein coding gene Chr19:26930344-26933199 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025431
protein coding gene Chr19:28147324-28150182 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022850
protein coding gene Chr19:25992145-25995014 (+)
CAST/EiJ MGP_CASTEiJ_G0024216
protein coding gene Chr19:26756110-26758969 (+)
CBA/J MGP_CBAJ_G0024724
protein coding gene Chr19:29485937-29488795 (+)
DBA/2J MGP_DBA2J_G0024856
protein coding gene Chr19:25970361-25973218 (+)
FVB/NJ MGP_FVBNJ_G0024818
protein coding gene Chr19:25820282-25823139 (+)
LP/J MGP_LPJ_G0024941
protein coding gene Chr19:27393371-27396228 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024845
protein coding gene Chr19:29411080-29413935 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025486
protein coding gene Chr19:26982458-26985313 (+)
PWK/PhJ MGP_PWKPhJ_G0023964
protein coding gene Chr19:25633125-25636047 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023768
protein coding gene Chr19:26234112-26236984 (+)
WSB/EiJ MGP_WSBEiJ_G0024283
protein coding gene Chr19:27014478-27017333 (+)



Homology
more
  • Human Ortholog
    PLPP6, phospholipid phosphatase 6
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PLPP6, phospholipid phosphatase 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA6J24.6, PDP1, PPAPDC2, PSDP
  • Links
    NCBI Gene ID: 403313
    neXtProt AC: NX_Q8IY26
    UniProt: Q8IY26

  • Chr Location
    chr9:4662294-4665274 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040105 Ensembl Gene Model | MGI Sequence Detail 2859 C57BL/6J ±  kb
transcript ENSMUST00000045674 Ensembl | MGI Sequence Detail 2859 Not Applicable  
polypeptide ENSMUSP00000047776 Ensembl | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 5
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:236757 West DB, et al., Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. PLoS Genet. 2016 Feb;12(2):e1005691

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory