Plpp6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plpp6
phospholipid phosphatase 6
MGI:1921661

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plpp6^{tm1.1(KOMP)Vlcg}/Plpp6^{tm1.1(KOMP)Vlcg} C57BL/6N-Plpp6^{tm1.1(KOMP)Vlcg}/Ucd	abnormal testis morphology	J:211773
	enlarged testis	J:211773
	increased mean platelet volume	J:211773
Plpp6^tm1Bdl/Plpp6^tm1Bdl C.Cg-Plpp6^tm1Bdl	abnormal dendritic cell physiology	J:329994
	abnormal lipid level	J:329994
	abnormal macropinocytosis	J:329994
	abnormal T-helper 2 cell differentiation	J:329994
	decreased cholesterol level	J:329994
	decreased circulating cholesterol level	J:329994
	decreased dendritic cell number	J:329994
	decreased IgE level	J:329994
	decreased level of surface class II molecules	J:329994
	decreased lipogenesis	J:329994
	decreased plasmacytoid dendritic cell number	J:329994
	decreased susceptibility to type I hypersensitivity reaction	J:329994
	increased dendritic cell number	J:329994
	increased plasmacytoid dendritic cell number	J:329994

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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