About   Help   FAQ
Ulk4
Gene Detail
Symbol

Name
ID
Ulk4
unc-51-like kinase 4
MGI:1921622
Synonyms
4932415A06Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
72.19 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:120960268-121277197 bp, - strand
From VEGA annotation of GRCm38

  316930 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ulk4

Human
homologs
Human Homolog ULK4, unc-51 like kinase 4
NCBI Gene ID 54986
neXtProt AC  NX_Q96C45
Human Synonyms  FAM7C1, REC01035
Human Chr (Location)  3p22.1; chr3:41246599-41962504 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null mutation exhibit reduced body size, hydrocephalus and dilation of brain ventricles and otitis media with most mice dieing before four months of age. Mice homozygous for a different knock-out allele exhibit partial agenesis of the corpus callosum.
 
Interactions
Ulk4 interacts with 333 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process cilium morphogenesis, corpus callosum development, ...
Component cellular_component
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
cDNA source data(50)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(50) cDNA(50)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000036158 (Evidence)
Ensembl Gene ModelENSMUSG00000040936 (Evidence)
Entrez Gene209012 (Evidence)
UniGene371804
EC2.7.11.1
Consensus CDS ProjectCCDS52967.1
International Mouse Knockout Project StatusUlk4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036158 VEGA Gene Model | MGI Sequence Detail 316930 C57BL/6J ±  kb
transcript OTTMUST00000092956 VEGA | MGI Sequence Detail 4103 Not Applicable 
polypeptide OTTMUSP00000051478 VEGA | MGI Sequence Detail 1275 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(12) UniProt(9)
Polymorphisms
SNPs within 2kb(2571 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2579)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000017080 serine/threonine-protein kinase ULK4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:211886 Lang B, et al., Recurrent deletions of ULK4 in schizophrenia: a gene crucial for neuritogenesis and neuronal motility. J Cell Sci. 2014 Feb 1;127(Pt 3):630-40
All references(29)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory