Ulk4
Gene Detail

Symbol Name ID

Ulk4 unc-51-like kinase 4 MGI:1921622

Synonyms

4932415A06Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 9

72.19 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr9:120960268-121277197 bp, - strand From VEGA annotation of GRCm38   316930 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ulk4

Human homologs

Human Homolog		ULK4, unc-51-like kinase 4 (C. elegans)
NCBI Gene ID		54986
neXtProt AC		NX_Q96C45
Human Synonyms		FAM7C1, REC01035
Human Chr (Location)		3p22.1; chr3:41288090-42003660 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)
 

Mice homozygous for a targeted null mutation exhibit reduced body size and hydrocephalus, and most die before four months of age. Dilation of brain ventricles and otitis media are also seen.

 
Human Diseases Modeled Using Mouse Ulk4 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	cilium morphogenesis, epithelial cilium movement, ...
Component	cellular_component
Function	ATP binding, kinase activity, ...

External Resources: FuncBase

Expression

cDNA source data(48)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(48) cDNA(48)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000036158 (Evidence)
Ensembl Gene Model	ENSMUSG00000040936 (Evidence)
Entrez Gene	209012 (Evidence)
UniGene	371804
DFCI	TC1581391, TC1586755, TC1629178
DoTS	DT.101399055, DT.110570566, DT.110570608, DT.55128574, DT.91332071, DT.91434743, DT.94229335
NIA Mouse Gene Index	U041112
EC	2.7.11.1
Consensus CDS Project	CCDS52967.1
International Mouse Knockout Project Status	Ulk4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000036158	VEGA Gene Model | MGI Sequence Detail	316930	C57BL/6J
transcript	OTTMUST00000092956	VEGA | MGI Sequence Detail	4103	Not Applicable
polypeptide	OTTMUSP00000051478	VEGA | MGI Sequence Detail	1275	Not Applicable

All sequences(59) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(1243 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011989	Armadillo-like helical
InterPro	IPR016024	Armadillo-type fold
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
Protein Ontology	PR:000017080	serine/threonine-protein kinase ULK4

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(29)