Slc6a19
Gene Detail

Symbol Name ID

Slc6a19 solute carrier family 6 (neurotransmitter transporter), member 19 MGI:1921588

Synonyms

4632401C08Rik, B<0>AT1

Feature Type

protein coding gene

Genetic Map

Chromosome 13

40.14 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr13:73679745-73704865 bp, - strand From VEGA annotation of GRCm38   25121 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:52819  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 3 zebrafish

Gene Tree: Slc6a19

Human homologs

Human Homolog		SLC6A19, solute carrier family 6 (neutral amino acid transporter), member 19
NCBI Gene ID		340024
neXtProt AC		NX_Q695T7
Human Synonyms		B0AT1, HND
Human Chr (Location)		5p15.33; chr5:1201710-1225232 (+)  GRCh37.p10
Disease Associations		(3) Diseases Associated with Human SLC6A19

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a knock-out allele exhibit decreased body weight and impaired amino acid absorption and excretion.

 
Human Diseases Modeled Using Mouse Slc6a19 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(1)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	amino acid transmembrane transport, amino acid transport, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	neurotransmitter:sodium symporter activity, neutral amino acid transmembrane transporter activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23

Assay Type	Results
RNA in situ	1

cDNA source data(29)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(31) cDNA(30) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000026285 (Evidence)
Ensembl Gene Model	ENSMUSG00000021565 (Evidence)
Entrez Gene	74338 (Evidence)
UniGene	271635
DFCI	TC1581859, TC1594380, TC1597423
DoTS	DT.101299807, DT.101366615, DT.110957128, DT.40165423
NIA Mouse Gene Index	U041171
Consensus CDS Project	CCDS26634.1
International Mouse Knockout Project Status	Slc6a19

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026285	VEGA Gene Model | MGI Sequence Detail	25121	C57BL/6J
transcript	OTTMUST00000065018	VEGA | MGI Sequence Detail	3936	Not Applicable
polypeptide	OTTMUSP00000032347	VEGA | MGI Sequence Detail	634	Not Applicable

All sequences(46) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(97 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000175	Sodium:neurotransmitter symporter
InterPro	IPR002438	Sodium:neurotransmitter symporter, orphan
Protein Ontology	PR:000015185	sodium-dependent neutral amino acid transporter B(0)

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187519 Fairweather SJ, et al., Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. Biochem J. 2012 Aug 15;446(1):135-48
All references(35)