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Slc6a19
Gene Detail
 Symbol
Name
ID
Slc6a19
solute carrier family 6 (neurotransmitter transporter), member 19
MGI:1921588
Synonyms 4632401C08Rik, B0AT1
Feature Type protein coding gene
Genetic Map
Chromosome 13
40.14 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:73679745-73704865 bp, - strand
From VEGA annotation of GRCm38

  25121 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:52819  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 3 zebrafish

Gene Tree: Slc6a19

Human
homologs
Human Homolog SLC6A19, solute carrier family 6 (neutral amino acid transporter), member 19
NCBI Gene ID 340024
neXtProt AC  NX_Q695T7
Human Synonyms  B0AT1, HND
Human Chr (Location)  5p15.33; chr5:1201595-1225117 (+)  GRCh38
Disease Associations  (3) Diseases Associated with Human SLC6A19
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased body weight and impaired amino acid absorption and excretion.
 
Human Diseases Modeled Using Mouse Slc6a19 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(1)
Interactions
Slc6a19 interacts with 282 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process amino acid transmembrane transport, amino acid transport, ...
Component brush border membrane, extracellular vesicular exosome, ...
Function neurotransmitter:sodium symporter activity, neutral amino acid transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (28)    Tissues (28)    Images (3)
Theiler Stages: 23, 26, 28
Assay TypeResults
RNA in situ 28
cDNA source data(29)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(31) cDNA(30) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026285 (Evidence)
Ensembl Gene ModelENSMUSG00000021565 (Evidence)
Entrez Gene74338 (Evidence)
UniGene271635
DFCITC1581859, TC1594380, TC1597423
DoTSDT.101299807, DT.101366615, DT.110957128, DT.40165423
NIA Mouse Gene IndexU041171
Consensus CDS ProjectCCDS26634.1
International Mouse Knockout Project StatusSlc6a19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026285 VEGA Gene Model | MGI Sequence Detail 25121 C57BL/6J ±  kb
transcript OTTMUST00000065018 VEGA | MGI Sequence Detail 3936 Not Applicable 
polypeptide OTTMUSP00000032347 VEGA | MGI Sequence Detail 634 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(115 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000175 Sodium:neurotransmitter symporter
InterPro IPR002438 Sodium:neurotransmitter symporter, orphan
Protein Ontology PR:000015185 sodium-dependent neutral amino acid transporter B(0)AT1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187519 Fairweather SJ, et al., Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. Biochem J. 2012 Aug 15;446(1):135-48
All references(38)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory