Sequence Detail

ID/Version

Q9D687 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Sodium-dependent neutral amino acid transporter B(0)AT1;AltName: Full=Solute carrier family 6 member 19;AltName: Full=System B(0) neutral amino acid transporter AT1;

Provider

SWISS-PROT

Sequence

Polypeptide 634 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc6a19	solute carrier family 6 (neurotransmitter transporter), member 19	18	99	5	11

Sequence references in MGI

J:90740 Broer A, et al., Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder. J Biol Chem. 2004 Jun 4;279(23):24467-76
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117490 Danilczyk U, et al., Essential role for collectrin in renal amino acid transport. Nature. 2006 Dec 21;444(7122):1088-91
J:117499 Bohmer C, et al., Characterization of mouse amino acid transporter B0AT1 (slc6a19). Biochem J. 2005 Aug 1;389(Pt 3):745-51
J:146850 Camargo SM, et al., Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology. 2009 Mar;136(3):872-82
J:175382 Broer A, et al., Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse. J Biol Chem. 2011 Jul 29;286(30):26638-51
J:187519 Fairweather SJ, et al., Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. Biochem J. 2012 Aug 15;446(1):135-48
J:257334 Fairweather SJ, et al., Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin. J Biol Chem. 2015 Oct 2;290(40):24308-25
J:259115 Kowalczuk S, et al., A protein complex in the brush-border membrane explains a Hartnup disorder allele. FASEB J. 2008 Aug;22(8):2880-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89