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Serpina3a
Gene Detail
 Symbol
Name
ID
Serpina3a
serine (or cysteine) peptidase inhibitor, clade A, member 3A
MGI:1921319
Synonyms 4933406L18Rik, alpha-1 antiproteinase,, antitrypsin
Feature Type protein coding gene
Genetic Map
Chromosome 12
53.34 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:104112724-104121896 bp, + strand
From VEGA annotation of GRCm38

  9173 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: serpin
Gene Tree: Serpina3a
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component extracellular region, extracellular space
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000035420 (Evidence)
Ensembl Gene ModelENSMUSG00000041536 (Evidence)
Entrez Gene74069 (Evidence)
UniGene159128
DFCITC1592217, TC1594356
DoTSDT.101177745, DT.55218590
NIA Mouse Gene IndexU014321
Consensus CDS ProjectCCDS49156.1
International Mouse Knockout Project StatusSerpina3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035420 VEGA Gene Model | MGI Sequence Detail 9173 C57BL/6J ±  kb
transcript OTTMUST00000090572 VEGA | MGI Sequence Detail 1269 Not Applicable 
polypeptide OTTMUSP00000049723 VEGA | MGI Sequence Detail 422 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(2)
Polymorphisms SNPs within 2kb(122 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015933 serine protease inhibitor A3A
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory