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Slc25a27 Gene Detail
Summary
  • Symbol
    Slc25a27
  • Name
    solute carrier family 25, member 27
  • Synonyms
    3632410G24Rik, 9430092A03Rik, D530043E16Rik, Ucp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921261
    NCBI Gene: 74011
  • Gene Overview
    MyGene.info: SLC25A27
Location & Maps
more
  • Sequence Map
    Chr17:43641900-43667015 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25116 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 19.75 cM, cytoband C
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC25A27, solute carrier family 25 member 27
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC25A27, solute carrier family 25 member 27
    Orthology source: HGNC, HomoloGene
  • Synonyms
    UCP4
  • Links
    NCBI Gene ID: 9481
    neXtProt AC: NX_O95847

  • Chr Location
    6p12.3; chr6:46652915-46678190 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    1
  • Gene trapped
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023912 Ensembl Gene Model | MGI Sequence Detail 25116 C57BL/6J ±  kb
transcript ENSMUST00000024705 Ensembl | MGI Sequence Detail 2687 Not Applicable  
polypeptide ENSMUSP00000024705 Ensembl | MGI Sequence Detail 322 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    227 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR023395 Mitochondrial carrier domain
    IPR018108 Mitochondrial substrate/solute carrier
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925827, MGI:2442063
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187672 Parker JA, et al., Integration of beta-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity. J Neurosci. 2012 Sep 5;32(36):12630-40

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory