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Slc25a27
Gene Detail
 Symbol
Name
ID
Slc25a27
solute carrier family 25, member 27
MGI:1921261
Synonyms 3632410G24Rik, 9430092A03Rik, D530043E16Rik, Ucp4
Feature Type protein coding gene
Genetic Map
Chromosome 17
19.75 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:43641900-43667015 bp, - strand
From NCBI annotation of GRCm38

  25116 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12523  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Slc25a27

Human
homologs
Human Homolog SLC25A27, solute carrier family 25, member 27
NCBI Gene ID 9481
neXtProt AC  NX_O95847
Human Synonyms  UCP4
Human Chr (Location)  6p12.3; chr6:46652915-46678190 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc25a27 interacts with 244 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cellular triglyceride homeostasis, negative regulation of apoptotic process, ...
Component apical part of cell, integral component of membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (89)    Tissues (39)    Images (23)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 89
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000023912 (Evidence)
Entrez Gene74011 (Evidence)
NIA Mouse Gene IndexU037825
Consensus CDS ProjectCCDS28798.1
International Mouse Knockout Project StatusSlc25a27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 74011 NCBI Gene Model | MGI Sequence Detail 25116 C57BL/6J ±  kb
transcript NM_028711 RefSeq | MGI Sequence Detail 2687 C57BL/6 
polypeptide NP_082987 RefSeq | MGI Sequence Detail 322 C57BL/6 

For the selected sequences
All sequences(48) RefSeq(26) UniProt(2)
Polymorphisms SNPs within 2kb(226 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015023 mitochondrial uncoupling protein 4
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187672 Parker JA, et al., Integration of beta-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity. J Neurosci. 2012 Sep 5;32(36):12630-40
All references(32)
Other
accession IDs
MGI:1925827, MGI:2442063

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory