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Slc25a27
Gene Detail
Symbol

Name
ID
Slc25a27
solute carrier family 25, member 27
MGI:1921261
Synonyms
3632410G24Rik, 9430092A03Rik, D530043E16Rik, Ucp4
Feature Type
protein coding gene
Genetic Map
Chromosome 17
19.75 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:43641900-43667015 bp, - strand
From Ensembl annotation of GRCm38

  25116 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12523  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC25A27
Gene Tree: Slc25a27

Human
homologs
SLC25A27, solute carrier family 25, member 27
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9481
neXtProt AC: NX_O95847

Human Synonyms: UCP4

Human Chr (Location): 6p12.3; chr6:46652915-46678190 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc25a27 interacts with 244 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cellular triglyceride homeostasis, negative regulation of apoptotic process, ...
Component apical part of cell, mitochondrion, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (89)    Tissues (39)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 89
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc25a27 ; ZFIN slc25a27    NEW 
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000023912 (Evidence)
Entrez Gene 74011 (Evidence)
NIA Mouse Gene Index U037825
Consensus CDS Project CCDS28798.1
International Mouse Phenotyping Consortium Status Slc25a27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023912 Ensembl Gene Model | MGI Sequence Detail 25116 C57BL/6J ±  kb
transcript ENSMUST00000024705 Ensembl | MGI Sequence Detail 2687 Not Applicable 
polypeptide ENSMUSP00000024705 Ensembl | MGI Sequence Detail 322 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(16) UniProt(2)
Polymorphisms
SNPs within 2kb(226 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015023 mitochondrial uncoupling protein 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187672 Parker JA, et al., Integration of beta-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity. J Neurosci. 2012 Sep 5;32(36):12630-40
All references(29)
Other
accession IDs
MGI:1925827, MGI:2442063

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory