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Stk36 Gene Detail
Summary
  • Symbol
    Stk36
  • Name
    serine/threonine kinase 36
  • Synonyms
    1700112N14Rik, Fused
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920831
    NCBI Gene: 269209
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:74640604-74676053 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 38.54 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    995 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920831
 protein coding gene Chr1:74640583-74676053 (+)
129S1/SvImJ ENSMUSG00200032847
 protein coding gene Chr1:72303684-72336300 (+)
A/J ENSMUSG00195008484
 protein coding gene Chr1:71728494-71761092 (+)
AKR/J ENSMUSG00220010363
 protein coding gene Chr1:71874332-71906937 (+)
BALB/cJ ENSMUSG00180017187
 protein coding gene Chr1:71987320-72022764 (+)
C3H/HeJ ENSMUSG00175015461
 protein coding gene Chr1:72128864-72161466 (+)
C57BL/6NJ ENSMUSG00215011930
 protein coding gene Chr1:72032645-72068099 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014270
 protein coding gene Chr1:68159506-68190835 (+)
CAST/EiJ ENSTCUG00005028214
 protein coding gene Chr1:71757331-71789792 (+)
CBA/J ENSMUSG00210035594
 protein coding gene Chr1:71813105-71845725 (+)
DBA/2J ENSMUSG00185030023
 protein coding gene Chr1:72907055-72939632 (+)
FVB/NJ ENSMUSG00205019204
 protein coding gene Chr1:71482253-71517701 (+)
JF1/MsJ ENSUMUG00000004997
 protein coding gene Chr1:71806999-71839705 (+)
LP/J ENSMUSG00230011232
 protein coding gene Chr1:72896851-72929455 (+)
NOD/ShiLtJ ENSMUSG00190034459
 protein coding gene Chr1:72038868-72071476 (+)
NZO/HlLtJ ENSMUSG00225039978
 protein coding gene Chr1:76111964-76144580 (+)
PWK/PhJ ENSLUMG00010013184
 protein coding gene Chr1:71390603-71423163 (+)
SPRET/EiJ ENSMSPG00010018044
 protein coding gene Chr1:73482165-73514536 (+)
WSB/EiJ ENSIUOG00005012356
 protein coding gene Chr1:71660670-71693278 (+)



Homology
more
  • Human Ortholog
    STK36, serine/threonine kinase 36
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STK36, serine/threonine kinase 36
  • Synonyms
    CILD46, FU
  • Links
    NCBI Gene ID: 27148
    UniProt: Q9NRP7

  • Chr Location
    2q35; chr2:218672052-218702717 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Stk36 mouse models; 1 with human STK36 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    36 phenotypes from 5 alleles in 5 genetic backgrounds
    3 phenotypes from multigenic genotypes
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Nullizygous mutations cause postnatal growth defects and lethality. Homozygotes for a null allele show hydrocephaly, cranial defects, otitis media and sterility. Homozygotes for another null allele show additional defects in lung and renal development, thymus and spleen atrophy, rhinitis and ataxia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    55
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    789
  • Tissues
    55
  • cDNA Data
    57
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033276 Ensembl Gene Model | MGI Sequence Detail 35450 C57BL/6J ±  kb
    transcript ENSMUST00000087183 Ensembl | MGI Sequence Detail 5245 Not Applicable  
    polypeptide ENSMUSP00000084430 Ensembl | MGI Sequence Detail 1316 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 57
      Primer pair 2
      Other 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 63
      Developmental Gene Expression 8
      Diseases 1
      Gene Ontology 15
      Phenotypes 25
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory