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Stk36 Gene Detail
Summary
  • Symbol
    Stk36
  • Name
    serine/threonine kinase 36
  • Synonyms
    1700112N14Rik, Fused
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920831
    NCBI Gene: 269209
  • Gene Overview
    MyGene.info: STK36
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr1:74601445-74636894 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35450 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.54 cM, cytoband C3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    STK36, serine/threonine kinase 36
  • Vertebrate Orthologs
    8
  • Human Ortholog
    STK36, serine/threonine kinase 36
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FU
  • Links
    NCBI Gene ID: 27148
    neXtProt AC: NX_Q9NRP7
    UniProt: Q9NRP7

  • Chr Location
    2q35; chr2:218672026-218702717 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Stk36 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    37 phenotypes from 5 alleles in 5 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Nullizygous mutations cause postnatal growth defects and lethality. Homozygotes for a null allele show hydrocephaly, cranial defects, otitis media and sterility. Homozygotes for another null allele show additional defects in lung and renal development, thymus and spleen atrophy, rhinitis and ataxia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000021747 VEGA Gene Model | MGI Sequence Detail 35450 C57BL/6J ±  kb
    transcript OTTMUST00000051614 VEGA | MGI Sequence Detail 5245 Not Applicable  
    polypeptide OTTMUSP00000024329 VEGA | MGI Sequence Detail 1316 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      294 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 50
      Primer pair 1
      Other 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 7
      Phenotypes 20
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:208762 Nozawa YI, et al., Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis. Dev Biol. 2014 Apr 15;388(2):170-80

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    10/09/2018
    MGI 6.12
    The Jackson Laboratory