About   Help   FAQ
Dhx30 Gene Detail
Summary
  • Symbol
    Dhx30
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 30
  • Synonyms
    2810477H02Rik, C130058C04Rik, Ddx30, helG
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920081
    NCBI Gene: 72831
Location & Maps
more
  • Sequence Map
    Chr9:110084320-110117830 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33511 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.86 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DHX30, DEAH-box helicase 30
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX30, DEAH-box helicase 30
    Orthology source: HomoloGene
  • Synonyms
    DDX30, RETCOR
  • Links
    NCBI Gene ID: 22907
    neXtProt AC: NX_Q7L2E3

  • Chr Location
    3p21.31; chr3:47802909-47850196 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 15779
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DHX30
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034137 VEGA Gene Model | MGI Sequence Detail 33511 C57BL/6J ±  kb
transcript OTTMUST00000086425 VEGA | MGI Sequence Detail 3806 Not Applicable  
polypeptide OTTMUSP00000046804 VEGA | MGI Sequence Detail 1223 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    66 from dbSNP Build 142
Protein
Information
less
  • UniProt
    11 Sequences
  • Protein Ontology
    PR:000030401 ATP-dependent RNA helicase DHX30
  • EC
  • InterPro Domains
    IPR011545 DEAD/DEAH box helicase domain
    IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 198
    cDNA 197
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142961, MGI:2143190, MGI:2444897
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:218057 Zheng HJ, et al., The Novel Helicase helG (DHX30) Is Expressed During Gastrulation in Mice and Has a Structure Similar to a Human DExH Box Helicase. Stem Cells Dev. 2015 Feb 1;24(3):372-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory