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Dhx30 Gene Detail
Summary
  • Symbol
    Dhx30
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 30
  • Synonyms
    2810477H02Rik, C130058C04Rik, Ddx30, helG
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920081
    NCBI Gene: 72831
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110084319-110117616 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920081
protein coding gene Chr9:110084319-110117830 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035341
protein coding gene Chr9:112214978-112250103 (-)
A/J MGP_AJ_G0035322
protein coding gene Chr9:108138121-108171603 (-)
AKR/J MGP_AKRJ_G0035253
protein coding gene Chr9:110820581-110853894 (-)
BALB/cJ MGP_BALBcJ_G0035317
protein coding gene Chr9:107880850-107912793 (-)
C3H/HeJ MGP_C3HHeJ_G0035025
protein coding gene Chr9:111308538-111342692 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035839
protein coding gene Chr9:115258415-115294573 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032725
protein coding gene Chr9:105363652-105394580 (-)
CAST/EiJ MGP_CASTEiJ_G0034331
protein coding gene Chr9:111105631-111144748 (-)
CBA/J MGP_CBAJ_G0034992
protein coding gene Chr9:119540926-119573696 (-)
DBA/2J MGP_DBA2J_G0035151
protein coding gene Chr9:107600672-107635038 (-)
FVB/NJ MGP_FVBNJ_G0035098
protein coding gene Chr9:106427813-106462579 (-)
LP/J MGP_LPJ_G0035230
protein coding gene Chr9:112508402-112543245 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035138
protein coding gene Chr9:120910362-120951841 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035859
protein coding gene Chr9:111136055-111171265 (-)
PWK/PhJ MGP_PWKPhJ_G0034038
protein coding gene Chr9:107837610-107871782 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033873
protein coding gene Chr9:111217667-111252996 (-)
WSB/EiJ MGP_WSBEiJ_G0034452
protein coding gene Chr9:111016428-111051571 (-)



Homology
more
  • Human Ortholog
    DHX30, DExH-box helicase 30
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX30, DExH-box helicase 30
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDX30, NEDMIAL, RETCOR
  • Links
    NCBI Gene ID: 22907
    neXtProt AC: NX_Q7L2E3
    UniProt: Q7L2E3

  • Chr Location
    3p21.31; chr3:47802909-47850196 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 15779
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DHX30
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit complete embryonic lethality associated with embryonic growth retardation, failure of initiation of embryo turning, and absence of organized somites and neural tube formation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72831 NCBI Gene Model | MGI Sequence Detail 33298 C57BL/6J ±  kb
    transcript NM_001252682 RefSeq | MGI Sequence Detail 4228 C57BL/6  
    polypeptide Q99PU8 UniProt | EBI | MGI Sequence Detail 1217 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 199
      cDNA 198
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2142961, MGI:2143190, MGI:2444897
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    03/19/2019
    MGI 6.13
    The Jackson Laboratory