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Tonsl Gene Detail
Summary
  • Symbol
    Tonsl
  • Name
    tonsoku-like, DNA repair protein
  • Synonyms
    2810439M11Rik, Nfkbil2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919999
    NCBI Gene: 72749
  • Gene Overview
    MyGene.info: TONSL
Location & Maps
more
  • Sequence Map
    Chr15:76626002-76639958 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13957 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.18 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TONSL, tonsoku-like, DNA repair protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TONSL, tonsoku-like, DNA repair protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    IKBR, NFKBIL2
  • Links
    NCBI Gene ID: 4796
    neXtProt AC: NX_Q96HA7

  • Chr Location
    8q24.3; chr8:144428780-144444488 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    3
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    5 involving Tonsl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035250 VEGA Gene Model | MGI Sequence Detail 13957 C57BL/6J ±  kb
transcript OTTMUST00000089893 VEGA | MGI Sequence Detail 4235 Not Applicable  
polypeptide OTTMUSP00000049174 VEGA | MGI Sequence Detail 1363 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    111 from dbSNP Build 142
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory