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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tonsl
tonsoku-like, DNA repair protein
MGI:1919999
11 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tonslem1(IMPC)Bay/Tonsl+
C57BL/6N-Tonslem1(IMPC)Bay/Bay 		abnormal retina vasculature morphology J:211773
increased heart left ventricle size J:211773
thick ventricular wall J:211773
Tonslem1(IMPC)Bay/Tonslem1(IMPC)Bay
C57BL/6N-Tonslem1(IMPC)Bay/Bay 		embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Tonslem1Tjch/Tonsl+
involves: C57BL/6 		no abnormal phenotype detected J:282817
Tonslem1Tjch/Tonslem1Tjch
involves: C57BL/6 		absent vitelline blood vessels J:282817
embryonic growth retardation J:282817
embryonic lethality during organogenesis, complete penetrance J:282817
internal hemorrhage J:282817
small visceral yolk sac J:282817
Tonslem2(IMPC)Bay/Tonslem2(IMPC)Bay
C57BL/6N-Tonslem2(IMPC)Bay/BayMmucd 		preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory