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Cdkn3 Gene Detail
Summary
  • Symbol
    Cdkn3
  • Name
    cyclin-dependent kinase inhibitor 3
  • Synonyms
    2410006H10Rik, KAP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919641
    NCBI Gene: 72391
  • Gene Overview
    MyGene.info: CDKN3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:46760465-46771530 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 24.28 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919641
protein coding gene Chr14:46760465-46771669 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021213
protein coding gene Chr14:40446227-40458057 (+)
A/J MGP_AJ_G0021160
protein coding gene Chr14:39240027-39250628 (+)
AKR/J MGP_AKRJ_G0021138
protein coding gene Chr14:40764712-40775310 (+)
BALB/cJ MGP_BALBcJ_G0021164
protein coding gene Chr14:39288848-39299449 (+)
C3H/HeJ MGP_C3HHeJ_G0020947
protein coding gene Chr14:40552603-40563207 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021598
protein coding gene Chr14:42201184-42212168 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019157
protein coding gene Chr14:38612069-38622963 (+)
CAST/EiJ MGP_CASTEiJ_G0020472
protein coding gene Chr14:37678716-37692996 (+)
CBA/J MGP_CBAJ_G0020913
protein coding gene Chr14:43532185-43542726 (+)
DBA/2J MGP_DBA2J_G0021036
protein coding gene Chr14:39140515-39151301 (+)
FVB/NJ MGP_FVBNJ_G0021021
protein coding gene Chr14:38878279-38888868 (+)
LP/J MGP_LPJ_G0021106
protein coding gene Chr14:40742351-40753335 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021046
protein coding gene Chr14:42906962-42917715 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021631
protein coding gene Chr14:40307500-40318098 (+)
PWK/PhJ MGP_PWKPhJ_G0020221
protein coding gene Chr14:36015875-36026879 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020045
protein coding gene Chr14:36443993-36455670 (+)
WSB/EiJ MGP_WSBEiJ_G0020528
protein coding gene Chr14:40415544-40426131 (+)



Homology
more
  • Human Ortholog
    CDKN3, cyclin dependent kinase inhibitor 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CDKN3, cyclin dependent kinase inhibitor 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDI1, CIP2, KAP, KAP1
  • Links
    NCBI Gene ID: 1033
    neXtProt AC: NX_Q16667
    UniProt: Q16667

  • Chr Location
    14q22.2; chr14:54396939-54420218 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72391 NCBI Gene Model | MGI Sequence Detail 11066 C57BL/6J ±  kb
transcript NM_001360041 RefSeq | MGI Sequence Detail 784 C57BL/6  
polypeptide Q810P3 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:206795 Khoury-Haddad H, et al., PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):E728-37

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory