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Lsm11 Gene Detail
Summary
  • Symbol
    Lsm11
  • Name
    U7 snRNP-specific Sm-like protein LSM11
  • Synonyms
    2210404M20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919540
    NCBI Gene: 72290
Location & Maps
more
  • Sequence Map
    Chr11:45928269-45944935 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16667 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    LSM11, LSM11, U7 small nuclear RNA associated
  • Vertebrate Orthologs
    8
  • Human Ortholog
    LSM11, LSM11, U7 small nuclear RNA associated
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 134353
    neXtProt AC: NX_P83369

  • Chr Location
    5q33.3; chr5:157743695-157760709 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Lsm11
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005480 VEGA Gene Model | MGI Sequence Detail 16667 C57BL/6J ±  kb
transcript OTTMUST00000012202 VEGA | MGI Sequence Detail 6453 Not Applicable  
polypeptide OTTMUSP00000005628 VEGA | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    261 from dbSNP Build 137
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000009956 U7 snRNA-associated Sm-like protein LSm11
  • InterPro Domains
    IPR010920 LSM domain
    IPR001163 LSM domain, eukaryotic/archaea-type
Molecular
Reagents
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  • All nucleic 52
    cDNA 52

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144458
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory