1600014C10Rik Gene Detail

Summary

• Symbol
  1600014C10Rik
• Name
  RIKEN cDNA 1600014C10 gene

• Feature Type
  protein coding gene
• IDs
  MGI:1919494
  NCBI Gene: 72244
• Alliance
  gene page
• Transcription Start Sites
  9 TSS

Location &
Maps

• Sequence Map
  Chr7:38183217-38197568 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 25.36 cM, cytoband B1
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  387 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919494	protein coding gene	Chr7:38183217-38197568 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0032101	protein coding gene	Chr7:37741740-37755885 (+)
A/J	MGP_AJ_G0032081	protein coding gene	Chr7:36684862-36701446 (+)
AKR/J	MGP_AKRJ_G0032014	protein coding gene	Chr7:37594775-37732026 (+)
BALB/cJ	MGP_BALBcJ_G0032088	protein coding gene	Chr7:36989836-37003984 (+)
C3H/HeJ	MGP_C3HHeJ_G0031805	protein coding gene	Chr7:38482870-38497004 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032565	protein coding gene	Chr7:39555876-39570240 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029598	protein coding gene	Chr7:37390881-37405414 (+)
CAST/EiJ	MGP_CASTEiJ_G0031140	protein coding gene	Chr7:29749083-29763180 (+)
CBA/J	MGP_CBAJ_G0031773	protein coding gene	Chr7:40822396-40839473 (+)
DBA/2J	MGP_DBA2J_G0031925	protein coding gene	Chr7:36511811-36526090 (+)
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0032002	protein coding gene	Chr7:38086357-38100519 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031918	protein coding gene	Chr7:39662812-39733889 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032580	protein coding gene	Chr7:37201291-37216498 (+)
PWK/PhJ	MGP_PWKPhJ_G0030862	protein coding gene	Chr7:29902862-29917167 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030697	protein coding gene	Chr7:26755465-26769925 (+)
WSB/EiJ	MGP_WSBEiJ_G0031250	protein coding gene	Chr7:37729677-37743823 (+)

Homology

• Human Ortholog
  C19orf12, chromosome 19 open reading frame 12

• Vertebrate Orthologs
  14

• Human Ortholog
  C19orf12, chromosome 19 open reading frame 12
  Orthology source: HomoloGene, HGNC
• Synonyms
  MPAN, NBIA3, NBIA4, SPG43
• Links
  HGNC:25443

  NCBI Gene ID: 83636

  neXtProt AC: NX_Q9NSK7

  UniProt: Q9NSK7

  
  
• Chr Location
  19q12; chr19:29698886-29715789 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 41744
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;3 chicken;3 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: C19orf12
• Gene Tree
  1600014C10Rik
  

Human Diseases

• Diseases
  2 with human C19orf12 associations

				Human Disease	Mouse Models
				hereditary spastic paraplegia 43 IDs hereditary spastic paraplegia 43       DOID:0110795 ICD10CM:G11.4 OMIM:615043 ORDO:320370
				neurodegeneration with brain iron accumulation 4 IDs neurodegeneration with brain iron accumulation 4       DOID:0110738 ICD10CM:G23.0 OMIM:614298 ORDO:289560

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  1
• Gene trapped
  4
• Targeted
  1
• Incidental Mutations
  CvDC
• Find Mice (IMSR)
  5 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  11
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  107
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN zgc:101715, zgc:112052

Interactions

• 1600014C10Rik interacts with 263 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  58
• RefSeq
  4
• UniProt
  3
• UniGene
  187554

• Ensembl
  ENSMUSG00000054676 (Evidence)
• NCBI Gene
  72244

Representative Sequences			Length	Strain/Species
genomic	72244	NCBI Gene Model | MGI Sequence Detail	14352	C57BL/6J
transcript	NM_001085385	RefSeq | MGI Sequence Detail	3357	C57BL/6
polypeptide	Q8WUR0	UniProt | EBI | MGI Sequence Detail	141	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR033369 Protein C19orf12 homologue

Molecular
Reagents

• All nucleic 107

  cDNA 107

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:2141949

References

• Summaries
  All 28

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 5
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for 1600014C10Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr65934	Chr7:38182788-38182822 (+)	-412 bp
Tssr65935	Chr7:38183185-38183199 (+)	-25 bp
Tssr65936	Chr7:38183224-38183278 (+)	34 bp
Tssr65937	Chr7:38183647-38183668 (+)	441 bp
Tssr65938	Chr7:38183750-38183757 (+)	537 bp
Tssr65939	Chr7:38183804-38183869 (+)	620 bp
Tssr65940	Chr7:38183876-38183885 (+)	664 bp
Tssr65941	Chr7:38186235-38186249 (+)	3,025 bp
Tssr65942	Chr7:38186254-38186262 (+)	3,041 bp