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Snx6 Gene Detail
Summary
  • Symbol
    Snx6
  • Name
    sorting nexin 6
  • Synonyms
    2010006G21Rik, 2610032J07Rik, 2810425K19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919433
    NCBI Gene: 72183
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:54746349-54795703 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 23.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    323 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919433
protein coding gene Chr12:54746339-54795750 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019738
protein coding gene Chr12:53691683-53738997 (-)
A/J MGP_AJ_G0019700
protein coding gene Chr12:51804449-51848105 (-)
AKR/J MGP_AKRJ_G0019671
protein coding gene Chr12:53351083-53392973 (-)
BALB/cJ MGP_BALBcJ_G0019678
protein coding gene Chr12:52087858-52128838 (-)
C3H/HeJ MGP_C3HHeJ_G0019481
protein coding gene Chr12:53461556-53505744 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020126
protein coding gene Chr12:55356247-55402112 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017749
protein coding gene Chr12:50072376-50113588 (-)
CAST/EiJ MGP_CASTEiJ_G0019034
protein coding gene Chr12:48470281-48511461 (-)
CBA/J MGP_CBAJ_G0019453
protein coding gene Chr12:57244017-57291416 (-)
DBA/2J MGP_DBA2J_G0019567
protein coding gene Chr12:51646127-51701653 (-)
FVB/NJ MGP_FVBNJ_G0019556
protein coding gene Chr12:51066218-51110767 (-)
LP/J MGP_LPJ_G0019639
protein coding gene Chr12:53754519-53801609 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019592
protein coding gene Chr12:58844120-58902525 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020164
protein coding gene Chr12:52838313-52890448 (-)
PWK/PhJ MGP_PWKPhJ_G0018801
protein coding gene Chr12:46221891-46265040 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018595
protein coding gene Chr12:47429166-47474699 (-)
WSB/EiJ MGP_WSBEiJ_G0019085
protein coding gene Chr12:53316757-53360298 (-)



Homology
more
  • Human Ortholog
    SNX6, sorting nexin 6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SNX6, sorting nexin 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MSTP010, TFAF2
  • Links
    NCBI Gene ID: 58533
    neXtProt AC: NX_Q9UNH7
    UniProt: Q9UNH7

  • Chr Location
    14q13.1; chr14:34561409-34630160 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000005656 Ensembl Gene Model | MGI Sequence Detail 49355 C57BL/6J ±  kb
transcript ENSMUST00000005798 Ensembl | MGI Sequence Detail 1928 Not Applicable  
polypeptide ENSMUSP00000005798 Ensembl | MGI Sequence Detail 406 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 7
Other
Accession IDs
less
MGI:1916480, MGI:1917093, MGI:2144946, MGI:2145122
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:240866 Niu Y, et al., Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory. Elife. 2017 Jan 30;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory