Snx6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Snx6
sorting nexin 6
MGI:1919433

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Snx6^em1(IMPC)J/Snx6^em1(IMPC)J C57BL/6NJ-Snx6^em1(IMPC)J/Mmjax	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
Snx6^tm1.1Nju/Snx6^tm1.1Nju Tg(Nes-cre)1Kln/0 involves: C57BL/6NTac * SJL	abnormal asymmetric synapse morphology	J:240866
	abnormal excitatory synapse morphology	J:240866
	abnormal spatial working memory	J:240866
	normal behavior/neurological phenotype	J:240866
	decreased dendritic spine density	J:240866
	impaired spatial learning	J:240866
	normal nervous system phenotype	J:240866
	reduced AMPA-mediated synaptic currents	J:240866

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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