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Chst14
Gene Detail
Symbol

Name
ID
Chst14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
MGI:1919386
Synonyms
2600016L03Rik, D4st1, D4ST-1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
59.73 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:118926496-118928585 bp, + strand
From VEGA annotation of GRCm38

  2090 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12443  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Chst14

Human
homologs
Human Homolog CHST14, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
NCBI Gene ID 113189
neXtProt AC  NX_Q8NCH0
Human Synonyms  ATCS, D4ST1, EDSMC1, HNK1ST
Human Chr (Location)  15q15.1; chr15:40470961-40473158 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CHST14
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit accelerated peripheral nerve regeneration, decreased body weight, premature death, fragile skin and background sensitive abnormal fertility, kinked tail and tooth growth.
 
Interactions
Chst14 interacts with 164 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (17)    Tissues (12)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 15
RT-PCR 2
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000015639 (Evidence)
Ensembl Gene ModelENSMUSG00000074916 (Evidence)
Entrez Gene72136 (Evidence)
DFCITC1576618
DoTSDT.490503, DT.101389415
NIA Mouse Gene IndexU002292
EC2.8.2.35
Consensus CDS ProjectCCDS16587.1
International Mouse Knockout Project StatusChst14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015639 VEGA Gene Model | MGI Sequence Detail 2090 C57BL/6J ±  kb
transcript OTTMUST00000037150 VEGA | MGI Sequence Detail 2090 Not Applicable 
polypeptide OTTMUSP00000016652 VEGA | MGI Sequence Detail 376 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018011 Carbohydrate sulfotransferase-related
InterPro IPR005331 Sulfotransferase
Protein Ontology PR:000005474 carbohydrate sulfotransferase 14
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203583 Akyuz N, et al., Dermatan 4-O-sulfotransferase1 ablation accelerates peripheral nerve regeneration. Exp Neurol. 2013 Sep;247:517-30
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory