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Ddhd2
Gene Detail
 Symbol
Name
ID
Ddhd2
DDHD domain containing 2
MGI:1919358
Synonyms 2010305K11Rik, SAMWD1
Feature Type protein coding gene
Genetic Map
Chromosome 8
14.17 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:25725324-25754280 bp, - strand
From NCBI annotation of GRCm38

  28957 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:66646  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ddhd2

Human
homologs
Human Homolog DDHD2, DDHD domain containing 2
NCBI Gene ID 23259
neXtProt AC  NX_O94830
Human Synonyms  iPLA(1)gamma, SAMWD1, SPG54
Human Chr (Location)  8p11.23; chr8:38231343-38262833 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human DDHD2
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ddhd2 interacts with 269 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process lipid catabolic process, lipid metabolic process
Component cytoplasm, Golgi apparatus, ...
Function 1-oxa-2-oxocycloheptane lactonase activity, 3,4-dihydrocoumarin hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(45)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(45)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000061313 (Evidence)
Entrez Gene72108 (Evidence)
UniGene246875
EC3.1.1.-
Consensus CDS ProjectCCDS52529.1
International Mouse Knockout Project StatusDdhd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 72108 NCBI Gene Model | MGI Sequence Detail 28957 C57BL/6J ±  kb
transcript NM_028102 RefSeq | MGI Sequence Detail 4267 C57BL/6 
polypeptide Q80Y98 UniProt | EBI | MGI Sequence Detail 699 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(16) UniProt(2)
Polymorphisms SNPs within 2kb(154 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004177 DDHD
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR021129 Sterile alpha motif, type 1
InterPro IPR004170 WWE domain
Protein Ontology PR:000006344 phospholipase DDHD2
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory