Elp6
Gene Detail

Symbol Name ID

Elp6 elongator acetyltransferase complex subunit 6 MGI:1919349

Synonyms

2610001P13Rik, 2610002I17Rik, Tmem103

Feature Type

protein coding gene

Genetic Map

Chromosome 9

59.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr9:110305192-110322092 bp, + strand From Ensembl annotation of GRCm38   16901 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9794  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: uncharacterized conserved protein, TMEM103 type
Gene Tree: Elp6

Human homologs

Human Homolog		ELP6, elongator acetyltransferase complex subunit 6
NCBI Gene ID		54859
neXtProt AC		NX_Q0PNE2
Human Synonyms		C3orf75, TMEM103
Human Chr (Location)		3p21.31; chr3:47537130-47555199 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(14) : Gene trapped(14)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	positive regulation of cell migration, regulation of transcription, DNA-dependent, ...
Component	Elongator holoenzyme complex
Function	molecular_function

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) cDNA(23)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000054836 (Evidence)
Entrez Gene	72341 (Evidence)
UniGene	374250
DFCI	TC1583120, TC1589664
DoTS	DT.40184039, DT.94132201, DT.94132203
NIA Mouse Gene Index	U011064
Consensus CDS Project	CCDS52937.1
International Mouse Knockout Project Status	Elp6

Sequences

Length	Strain/Species
genomic	ENSMUSG00000054836	Ensembl Gene Model | MGI Sequence Detail	16901	C57BL/6J
transcript	ENSMUST00000068071	Ensembl | MGI Sequence Detail	2054	Not Applicable
polypeptide	ENSMUSP00000069017	Ensembl | MGI Sequence Detail	266	Not Applicable

All sequences(24) RefSeq(3) UniProt(1)

Polymorphisms

SNPs(65 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR018627	Uncharacterised protein family UPF0405
Protein Ontology	PR:000030812	elongator complex protein 6

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187591 Close P, et al., DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator. J Biol Chem. 2012 Sep 21;287(39):32535-45
All references(32)

Other accession IDs

MGI:1919591, MGI:2143264