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Trmu
Gene Detail
 Symbol
Name
ID
Trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
MGI:1919276
Synonyms 1110005N20Rik, 1600025P05Rik, Trmt1
Feature Type protein coding gene
Genetic Map
Chromosome 15
40.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:85879312-85897394 bp, + strand
From VEGA annotation of GRCm38

  18083 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5589  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: S-adenosyl-L-methionine dependent tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
Gene Tree: Trmu

Human
homologs
Human Homolog TRMU, tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
NCBI Gene ID 55687
neXtProt AC  NX_O75648
Human Synonyms  MTO2, MTU1, TRMT, TRMT1, TRNT1
Human Chr (Location)  22q13; chr22:46335401-46357340 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human TRMU
Alleles
and
phenotypes
All alleles(3) : Targeted(1) Gene trapped(2)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process tRNA processing
Component cytoplasm, mitochondrion
Function ATP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
cDNA source data(36)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(38) cDNA(38)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034977 (Evidence)
Ensembl Gene ModelENSMUSG00000022386 (Evidence)
Entrez Gene72026 (Evidence)
UniGene158211
DFCITC1580950, TC1638439, TC1731314, TC1754200
DoTSDT.101721729, DT.40167398, DT.94148232
NIA Mouse Gene IndexU016533
EC2.8.1.-
Consensus CDS ProjectCCDS27726.1
International Mouse Knockout Project StatusTrmu
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034977 VEGA Gene Model | MGI Sequence Detail 18083 C57BL/6J ±  kb
transcript OTTMUST00000088943 VEGA | MGI Sequence Detail 1526 Not Applicable 
polypeptide OTTMUSP00000048548 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(13) UniProt(4)
Polymorphisms SNPs within 2kb(205 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023382 Adenine nucleotide alpha hydrolase-like domains
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
InterPro IPR004506 tRNA-specific 2-thiouridylase
Protein Ontology PR:000016686 mitochondrial tRNA-specific 2-thiouridylase 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(32)
Other
accession IDs
MGI:1915704, MGI:2145971

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory