About   Help   FAQ
Nup93 Gene Detail
Summary
  • Symbol
    Nup93
  • Name
    nucleoporin 93
  • Synonyms
    2410008G02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919055
    NCBI Gene: 71805
  • Gene Overview
    MyGene.info: NUP93
Location & Maps
more
  • Sequence Map
    Chr8:94214564-94317227 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      102664 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 46.40 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NUP93, nucleoporin 93
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP93, nucleoporin 93
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NIC96, NPHS12
  • Links
    NCBI Gene ID: 9688
    neXtProt AC: NX_Q8N1F7

  • Chr Location
    16q13; chr16:56730105-56844950 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 40971
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NUP93
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human NUP93 associations

Human Disease Mouse Models
       Nephrotic Syndrome, Type 12; NPHS12   OMIM: 616892
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000061621 VEGA Gene Model | MGI Sequence Detail 102664 C57BL/6J ±  kb
transcript OTTMUST00000150342 VEGA | MGI Sequence Detail 2928 Not Applicable  
polypeptide OTTMUSP00000077952 VEGA | MGI Sequence Detail 819 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    499 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:233606 Braun DA, et al., Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome. Nat Genet. 2016 Apr;48(4):457-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/22/2016
MGI 6.06
The Jackson Laboratory