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Vps11 Gene Detail
Summary
  • Symbol
    Vps11
  • Name
    VPS11, CORVET/HOPS core subunit
  • Synonyms
    1200011A11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918982
    NCBI Gene: 71732
  • Gene Overview
    MyGene.info: VPS11
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr9:44347881-44361672 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13792 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 24.84 cM, cytoband B
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    VPS11, VPS11, CORVET/HOPS core subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VPS11, VPS11, CORVET/HOPS core subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    END1, HLD12, hVPS11, PEP5, RNF108
  • Links
    NCBI Gene ID: 55823
    neXtProt AC: NX_Q9H270
    UniProt: Q9H270

  • Chr Location
    11q23.3; chr11:119067752-119081978 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human VPS11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 71732 NCBI Gene Model | MGI Sequence Detail 13792 C57BL/6J ±  kb
transcript NM_027889 RefSeq | MGI Sequence Detail 3194 Not Specified  
polypeptide Q91W86 UniProt | EBI | MGI Sequence Detail 941 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    83 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000017318 vacuolar protein sorting-associated protein 11
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR000547 Clathrin, heavy chain/VPS, 7-fold repeat
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR016528 Vacuolar protein sorting-associated protein 11
    IPR024763 Vacuolar protein sorting protein 11, C-terminal
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
Molecular
Reagents
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  • All nucleic 88
    cDNA 88

    Microarray probesets 6
References
more
  • Summaries
    All 34
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:222663 Perini ED, et al., Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations. Traffic. 2014 Dec;15(12):1366-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory