Cyp2u1
Gene Detail

Symbol Name ID

Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 MGI:1918769

Synonyms

8430436A10Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 3

60.89 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:131290491-131303227 bp, - strand From NCBI annotation of GRCm38   12737 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:77704  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2u1

Human homologs

Human Homolog		CYP2U1, cytochrome P450, family 2, subfamily U, polypeptide 1
NCBI Gene ID		113612
neXtProt AC		NX_Q7Z449
Human Synonyms		P450TEC, SPG49, SPG56
Human Chr (Location)		4q25; chr4:108852717-108874613 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP2U1

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, integral to membrane, ...
Function	aromatase activity, electron carrier activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	94
RT-PCR	12

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) Genomic(1) cDNA(4) Primer pair(1) Other(2)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000027983 (Evidence)
Entrez Gene	71519 (Evidence)
DFCI	TC1586276, TC1594386, TC1646195
DoTS	DT.101351366, DT.55120284, DT.91330131, DT.97358343
EC	1.14.14.1
Consensus CDS Project	CCDS51069.1
International Mouse Knockout Project Status	Cyp2u1

Sequences

Length	Strain/Species
genomic	71519	NCBI Gene Model | MGI Sequence Detail	12737	C57BL/6J
transcript	NM_027816	RefSeq | MGI Sequence Detail	2331	Not Specified
polypeptide	Q9CX98	UniProt | EBI | MGI Sequence Detail	530	Not Applicable

All sequences(23) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(54 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008069	Cytochrome P450, E-class, group I, CYP2D-like
Protein Ontology	PR:000006127	cytochrome P450 2U1

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)