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Cyp2u1
Gene Detail
 Symbol
Name
ID
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
MGI:1918769
Synonyms 8430436A10Rik
Feature Type protein coding gene
Genetic Map
Chromosome 3
60.89 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:131290491-131303227 bp, - strand
From NCBI annotation of GRCm38

  12737 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77704  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2u1

Human
homologs
Human Homolog CYP2U1, cytochrome P450, family 2, subfamily U, polypeptide 1
NCBI Gene ID 113612
neXtProt AC  NX_Q7Z449
Human Synonyms  P450TEC, SPG49, SPG56
Human Chr (Location)  4q25; chr4:107931561-107953461 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP2U1
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, integral component of membrane, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 94
RT-PCR 12
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(4) Primer pair(1) Other(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000027983 (Evidence)
Entrez Gene71519 (Evidence)
DFCITC1586276, TC1594386, TC1646195
DoTSDT.101351366, DT.55120284, DT.91330131, DT.97358343
EC1.14.14.1
Consensus CDS ProjectCCDS51069.1
International Mouse Knockout Project StatusCyp2u1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 71519 NCBI Gene Model | MGI Sequence Detail 12737 C57BL/6J ±  kb
transcript NM_027816 RefSeq | MGI Sequence Detail 2331 Not Specified 
polypeptide Q9CX98 UniProt | EBI | MGI Sequence Detail 530 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(3) UniProt(1)
Polymorphisms SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Protein Ontology PR:000006127 cytochrome P450 2U1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory