About   Help   FAQ
Sept12
Gene Detail
Symbol

Name
ID
Sept12
septin 12
MGI:1918339
Synonyms
1700028G04Rik, 4933413B09Rik, Septin12
Feature Type
protein coding gene
Genetic Map
Chromosome 16
2.49 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:4986858-4997852 bp, - strand
From NCBI annotation of GRCm38

  10995 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69435  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SEPT12
Protein SuperFamily: septin
Gene Tree: Sept12

Human
homologs
SEPT12, septin 12
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 124404
neXtProt AC: NX_Q8IYM1

Human Synonyms: SPGF10

Human Chr (Location): 16p13.3; chr16:4777609-4788521 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SEPT12

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Chimeric male mice are sterile.
 
Interactions
Sept12 interacts with 203 markers (Mir1b, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component microtubule cytoskeleton, midbody, ...
Function GTP binding, protein homodimerization activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sept12    NEW 
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000022542 (Evidence)
Entrez Gene 71089 (Evidence)
DFCI TC1585452, TC1705993
DoTS DT.101364521, DT.103559967, DT.94156505
NIA Mouse Gene Index U036756
Consensus CDS Project CCDS27929.1
International Mouse Phenotyping Consortium Status Sept12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 71089 NCBI Gene Model | MGI Sequence Detail 10995 C57BL/6J ±  kb
transcript NM_027669 RefSeq | MGI Sequence Detail 2576 C57BL/6 
polypeptide NP_081945 RefSeq | MGI Sequence Detail 317 C57BL/6 

For the selected sequences
All sequences(31) RefSeq(12) UniProt(3)
Polymorphisms
SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
Protein Ontology PR:000014651 septin-12
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(23)
Other
accession IDs
MGI:1922898

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory