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Spag9
Gene Detail
Symbol

Name
ID
Spag9
sperm associated antigen 9
MGI:1918084
Synonyms
3110018C07Rik, 4733401I23Rik, 4831406C20Rik, JIP4, JLP, Mapk8ip4, syd1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
58.90 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:93996091-94126085 bp, + strand
From VEGA annotation of GRCm38

  129995 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2954  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Spag9

Human
homologs
Human Homolog SPAG9, sperm associated antigen 9
NCBI Gene ID 9043
neXtProt AC  NX_O60271
Human Synonyms  CT89, HLC4, HLC-6, JIP4, JIP-4, JLP, PHET, PIG6
Human Chr (Location)  17q21.33; chr17:50962174-51120865 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Chemically induced (ENU)(1) Gene trapped(4) Targeted(4)
Genomic Mutations involving Spag9 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Male mice homozygous for a null mutation display reduced fertility with oligoasthenozoospermia.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Spag9 interacts with 396 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process activation of JUN kinase activity, activation of MAPK activity, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function JUN kinase binding, kinesin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (110)    Tissues (37)    Images (40)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 107
Northern blot 3
cDNA source data(24)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) cDNA(25) Other(1)
Microarray probesets(5)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001645 VEGA Gene Model | MGI Sequence Detail 129995 C57BL/6J ±  kb
transcript OTTMUST00000003239 VEGA | MGI Sequence Detail 7340 Not Applicable 
polypeptide OTTMUSP00000001565 VEGA | MGI Sequence Detail 1307 Not Applicable 

For the selected sequences
All sequences(140) RefSeq(34) UniProt(11)
Polymorphisms
SNPs within 2kb(1109 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1111)
Protein-related
information
ResourceIDDescription
InterPro IPR019143 JNK/Rab-associated protein-1, N-terminal
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000015463 C-Jun-amino-terminal kinase-interacting protein 4
References
(Earliest) J:70979 Bowman AB, et al., Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 2000 Nov 10;103(4):583-94
(Latest) J:209131 Saba R, et al., CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81
All references(58)
Other
accession IDs
MGI:1920413, MGI:1924388, MGI:2144568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory