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Spag9
Gene Detail
Symbol

Name
ID
Spag9
sperm associated antigen 9
MGI:1918084
Synonyms
3110018C07Rik, 4733401I23Rik, 4831406C20Rik, JIP4, JLP, Mapk8ip4, syd1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
58.90 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:93996091-94126085 bp, + strand
From VEGA annotation of GRCm38

  129995 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2954  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Spag9

Human
homologs
Human Homolog   SPAG9, sperm associated antigen 9
NCBI Gene ID 9043
neXtProt AC  NX_O60271
Human Synonyms  CT89, HLC4, HLC6, HLC-6, JIP4, JIP-4, JLP, PHET, PIG6
Human Chr (Location)  17q21.33; chr17:50962174-51120865 (-)  GRCh38.p2
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Chemically induced (ENU)(1) Gene trapped(4) Targeted(5)
Genomic Mutations involving Spag9 (3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Male mice homozygous for a null mutation display reduced fertility with oligoasthenozoospermia.
 
Mutations Annotated to Human Diseases (1)   
Interactions
Spag9 interacts with 395 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process activation of JUN kinase activity, activation of MAPK activity, ...
Component cytoplasm, extracellular exosome, ...
Function JUN kinase binding, kinesin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (110)    Tissues (37)    Images (40)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 107
Northern blot 3
cDNA source data(25)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(26) Other(1)
Microarray probesets(5)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001645 VEGA Gene Model | MGI Sequence Detail 129995 C57BL/6J ±  kb
transcript OTTMUST00000003239 VEGA | MGI Sequence Detail 7340 Not Applicable 
polypeptide OTTMUSP00000001565 VEGA | MGI Sequence Detail 1307 Not Applicable 

For the selected sequences
All sequences(143) RefSeq(36) UniProt(11)
Polymorphisms
SNPs within 2kb(1109 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1111)
Protein-related
information
ResourceIDDescription
InterPro IPR019143 JNK/Rab-associated protein-1, N-terminal
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000015463 C-Jun-amino-terminal kinase-interacting protein 4
References
(Earliest) J:70979 Bowman AB, et al., Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 2000 Nov 10;103(4):583-94
(Latest) J:217384 Suzuki A, et al., Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells. Biol Open. 2014;3(12):1207-16
All references(63)
Other
accession IDs
MGI:1920413, MGI:1924388, MGI:2144568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/21/2015
MGI 5.21
The Jackson Laboratory