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Stk26 Gene Detail
Summary
  • Symbol
    Stk26
  • Name
    serine/threonine kinase 26
  • Synonyms
    2610018G03Rik, Mst4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917665
    NCBI Gene: 70415
  • Gene Overview
    MyGene.info: STK26
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:50841174-50893103 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 27.50 cM, cytoband A3.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917665
protein coding gene ChrX:50841047-50893103 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035708
protein coding gene ChrX:45985933-46038484 (+)
A/J MGP_AJ_G0035691
protein coding gene ChrX:45857754-45917975 (+)
AKR/J MGP_AKRJ_G0035611
protein coding gene ChrX:47122914-47175326 (+)
BALB/cJ MGP_BALBcJ_G0035677
protein coding gene ChrX:45456957-45509066 (+)
C3H/HeJ MGP_C3HHeJ_G0035381
protein coding gene ChrX:46253780-46312287 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036206
protein coding gene ChrX:47098736-47151484 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033058
protein coding gene ChrX:43431689-43483561 (+)
CAST/EiJ MGP_CASTEiJ_G0034672
protein coding gene ChrX:33710178-33764919 (+)
CBA/J MGP_CBAJ_G0035355
protein coding gene ChrX:48385347-48437918 (+)
DBA/2J MGP_DBA2J_G0035510
protein coding gene ChrX:45695235-45746961 (+)
FVB/NJ MGP_FVBNJ_G0035458
protein coding gene ChrX:45399425-45451591 (+)
LP/J MGP_LPJ_G0035597
protein coding gene ChrX:46325869-46383612 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035497
protein coding gene ChrX:49926850-49980765 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036224
protein coding gene ChrX:45888515-45941398 (+)
PWK/PhJ MGP_PWKPhJ_G0034371
protein coding gene ChrX:33232920-33285403 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034216
protein coding gene ChrX:34494221-34548494 (+)
WSB/EiJ MGP_WSBEiJ_G0034816
protein coding gene ChrX:45438286-45492484 (+)



Homology
more
  • Human Ortholog
    STK26, serine/threonine kinase 26
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STK26, serine/threonine kinase 26
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MASK, MST4
  • Links
    NCBI Gene ID: 51765
    neXtProt AC: NX_Q9P289
    UniProt: Q9P289

  • Chr Location
    Xq26.2; chrX:132023217-132075943 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70415 NCBI Gene Model | MGI Sequence Detail 51930 C57BL/6J ±  kb
transcript NM_001313744 RefSeq | MGI Sequence Detail 3352 C57BL/6  
polypeptide Q99JT2 UniProt | EBI | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR035056 MST4, kinase domain
    IPR017441 Protein kinase, ATP binding site
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Molecular
Reagents
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  • All nucleic 37
    cDNA 36
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244663 Jiao S, et al., The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. Nat Immunol. 2015 Mar;16(3):246-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory