Stk26 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stk26
serine/threonine kinase 26
MGI:1917665

18 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Lgr5^{tm1(cre/ERT2)Cle}/\Lgr5⁺ \Stk26^tm2.1Zzh/\Stk26^tm2.1Zzh involves: 129P2/OlaHsd * C57BL/6	abnormal enterocyte proliferation	J:322311
\Sox9^{em1(cre/ERT2)Tchn}/\Sox9⁺ \Stk26^tm2.1Zzh/\Stk26^tm2.1Zzh involves: 129P2/OlaHsd * C57BL/6	abnormal enterocyte proliferation	J:322311
	decreased incidence of tumors by chemical induction	J:322311
\Sox9^{em1(cre/ERT2)Tchn}/\Sox9⁺ \Stk26^tm2.1Zzh/\Stk26^tm2.1Zzh involves: C57BL/6 * SJL	increased incidence of tumors by chemical induction	J:322311
\Stk26^tm1.1Zzh/\Stk26⁺ \Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/\Ndor1⁺ involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL	increased incidence of tumors by chemical induction	J:289548
\Stk26^tm1.1Zzh/\Stk26^tm1.1Zzh \Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/\Ndor1⁺ involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL	increased incidence of tumors by chemical induction	J:289548
\Stk26^{tm1b(EUCOMM)Hmgu}/Y C57BL/6N-Stk26^{tm1b(EUCOMM)Hmgu}/Ccpcz	abnormal pancreas morphology	J:211773
	abnormal thyroid gland morphology	J:211773
	decreased mean platelet volume	J:211773
	enlarged pancreas	J:211773
	enlarged thyroid gland	J:211773
	increased NK T cell number	J:211773
\Stk26^{tm1b(EUCOMM)Hmgu}/\Stk26^{tm1b(EUCOMM)Hmgu} C57BL/6N-Stk26^{tm1b(EUCOMM)Hmgu}/Ccpcz	abnormal adrenal gland morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal vertebral arch morphology	J:211773
	decreased circulating creatinine level	J:211773
	decreased mean platelet volume	J:211773
	decreased monocyte cell number	J:211773
	enlarged adrenal glands	J:211773
\Stk26^tm2.1Zzh/\Stk26^tm2.1Zzh involves: 129P2/OlaHsd * C57BL/6	abnormal enterocyte proliferation	J:322311
	abnormal intestinal goblet cell morphology	J:322311
	decreased Paneth cell number	J:322311
	decreased small intestine length	J:322311

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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