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Tlcd2 Gene Detail
Summary
  • Symbol
    Tlcd2
  • Name
    TLC domain containing 2
  • Synonyms
    2010305C02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917141
    NCBI Gene: 380712
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:75468024-75470899 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 45.91 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917141
protein coding gene Chr11:75461715-75470899 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018713
protein coding gene Chr11:76208791-76217878 (+)
A/J MGP_AJ_G0018679
protein coding gene Chr11:73377170-73386144 (+)
AKR/J MGP_AKRJ_G0018649
protein coding gene Chr11:75596980-75608887 (+)
BALB/cJ MGP_BALBcJ_G0018653
protein coding gene Chr11:73748370-73757955 (+)
C3H/HeJ MGP_C3HHeJ_G0018466
protein coding gene Chr11:75613842-75624743 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019104
protein coding gene Chr11:78594317-78603169 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016739
protein coding gene Chr11:70387104-70398379 (+)
CAST/EiJ MGP_CASTEiJ_G0018020
protein coding gene Chr11:76006781-76016603 (+)
CBA/J MGP_CBAJ_G0018436
protein coding gene Chr11:82046619-82060432 (+)
DBA/2J MGP_DBA2J_G0018545
protein coding gene Chr11:72981951-72991039 (+)
FVB/NJ MGP_FVBNJ_G0018535
protein coding gene Chr11:72541698-72551408 (+)
LP/J MGP_LPJ_G0018616
protein coding gene Chr11:76798358-76807232 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018561
protein coding gene Chr11:82612442-82621297 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019144
protein coding gene Chr11:75806173-75818458 (+)
PWK/PhJ MGP_PWKPhJ_G0017791
protein coding gene Chr11:73677642-73686532 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017582
protein coding gene Chr11:75359222-75368019 (+)
WSB/EiJ MGP_WSBEiJ_G0018073
protein coding gene Chr11:75613403-75624115 (+)



Homology
more
  • Human Ortholog
    TLCD2, TLC domain containing 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TLCD2, TLC domain containing 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 727910
    neXtProt AC: NX_A6NGC4
    UniProt: A6NGC4

  • Chr Location
    17p13.3; chr17:1702790-1710368 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Tlcd2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380712 NCBI Gene Model | MGI Sequence Detail 2876 C57BL/6J ±  kb
transcript NM_027249 RefSeq | MGI Sequence Detail 1424 C57BL/6  
polypeptide Q8VC26 UniProt | EBI | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory