About   Help   FAQ
Cyp2c66 Gene Detail
Summary
  • Symbol
    Cyp2c66
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 66
  • Synonyms
    2010301M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917138
    NCBI Gene: 69888
  • Gene Overview
    MyGene.info: CYP2C9
Location & Maps
more
  • Sequence Map
    Chr19:39113898-39187072 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      73175 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 33.75 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
    Orthology source: HomoloGene
  • Synonyms
    CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
  • Links
    NCBI Gene ID: 1559
    neXtProt AC: NX_P11712

  • Chr Location
    10q24; chr10:94938658-94989391 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CYP2C9 associations

Human Disease Mouse Models
       Coumarin Resistance   OMIM: 122700
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028352 VEGA Gene Model | MGI Sequence Detail 73175 C57BL/6J ±  kb
transcript OTTMUST00000070273 VEGA | MGI Sequence Detail 1630 Not Applicable  
polypeptide OTTMUSP00000035784 VEGA | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    149 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/22/2016
MGI 6.04
The Jackson Laboratory