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Cyp2c66
Gene Detail
 Symbol
Name
ID
Cyp2c66
cytochrome P450, family 2, subfamily c, polypeptide 66
MGI:1917138
Synonyms 2010301M18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 19
33.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:39113898-39187072 bp, + strand
From VEGA annotation of GRCm38

  73175 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110445  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 4 cattle

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c66

Human
homologs
Human Homolog CYP2C19, cytochrome P450, family 2, subfamily C, polypeptide 19
NCBI Gene ID 1557
neXtProt AC  NX_P33261
Human Synonyms  CPCJ, CYP2C, P450C2C, P450IIC19
Human Chr (Location)  10q24; chr10:94762706-94852914 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP2C19
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process hematopoietic progenitor cell differentiation, oxidation-reduction process
Component cellular_component
Function enzyme binding, heme binding, ...
External Resources: FuncBase
Expression
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000028352 (Evidence)
Ensembl Gene ModelENSMUSG00000067229 (Evidence)
Entrez Gene69888 (Evidence)
UniGene271190
NIA Mouse Gene IndexU131204
Consensus CDS ProjectCCDS29792.1
International Mouse Knockout Project StatusCyp2c66
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028352 VEGA Gene Model | MGI Sequence Detail 73175 C57BL/6J ±  kb
transcript OTTMUST00000070273 VEGA | MGI Sequence Detail 1630 Not Applicable 
polypeptide OTTMUSP00000035784 VEGA | MGI Sequence Detail 490 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(157 from dbSNP Build 137)    SNPs within 2kb including multiple locations(159)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006117 cytochrome P450 2C18
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory