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Cyp2c66 Gene Detail
Summary
  • Symbol
    Cyp2c66
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 66
  • Synonyms
    2010301M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917138
    NCBI Gene: 69888
  • Gene Overview
    MyGene.info: CYP2C9
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39113898-39186756 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 33.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917138
protein coding gene Chr19:39113898-39187072 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025099
protein coding gene Chr19:38235643-38323722 (+)
A/J MGP_AJ_G0025075
protein coding gene Chr19:36378430-36436346 (+)
AKR/J MGP_AKRJ_G0025043
protein coding gene Chr19:37591977-37649248 (+)
BALB/cJ MGP_BALBcJ_G0025073
protein coding gene Chr19:36472394-36534152 (+)
C3H/HeJ MGP_C3HHeJ_G0024832
protein coding gene Chr19:37694078-37743644 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025514
protein coding gene Chr19:39294060-39358933 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022933
protein coding gene Chr19:35627652-35658532 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0024809
protein coding gene Chr19:41200761-41250580 (+)
DBA/2J MGP_DBA2J_G0024941
protein coding gene Chr19:36205708-36264511 (+)
FVB/NJ MGP_FVBNJ_G0024902
protein coding gene Chr19:36028904-36090421 (+)
LP/J MGP_LPJ_G0025027
protein coding gene Chr19:38322416-38367879 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024933
protein coding gene Chr19:40875339-40975546 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025572
protein coding gene Chr19:37709264-37756251 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0024365
protein coding gene Chr19:37746229-37861457 (+)



Homology
more
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
    Orthology source: HomoloGene
  • Synonyms
    CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
  • Links
    NCBI Gene ID: 1559
    neXtProt AC: NX_P11712
    UniProt: P11712

  • Chr Location
    10q23.33; chr10:94905867-94989395 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69888 NCBI Gene Model | MGI Sequence Detail 72859 C57BL/6J ±  kb
transcript NM_001011707 RefSeq | MGI Sequence Detail 1630 BALB/c  
polypeptide NP_001011707 RefSeq | MGI Sequence Detail 490 BALB/c  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR036396 Cytochrome P450 superfamily
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory