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Slurp2 Gene Detail
Summary
  • Symbol
    Slurp2
  • Name
    secreted Ly6/Plaur domain containing 2
  • Synonyms
    2300005B03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916712
    NCBI Gene: 69462
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:74614688-74618536 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916712
 protein coding gene Chr15:74614613-74618542 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021935
 protein coding gene Chr15:74524714-74529266 (-)
A/J MGP_AJ_G0021894
 protein coding gene Chr15:71866597-71870526 (-)
AKR/J MGP_AKRJ_G0021876
 protein coding gene Chr15:73707123-73711052 (-)
BALB/cJ MGP_BALBcJ_G0021901
 protein coding gene Chr15:71878074-71882003 (-)
C3H/HeJ MGP_C3HHeJ_G0021674
 protein coding gene Chr15:73861466-73865395 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022341
 protein coding gene Chr15:77342442-77346371 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019877
 protein coding gene Chr15:68278636-68282570 (-)
CAST/EiJ MGP_CASTEiJ_G0021193
 protein coding gene Chr15:74683444-74687373 (-)
CBA/J MGP_CBAJ_G0021640
 protein coding gene Chr15:79875149-79879078 (-)
DBA/2J MGP_DBA2J_G0021765
 protein coding gene Chr15:71465020-71468949 (-)
FVB/NJ MGP_FVBNJ_G0021747
 protein coding gene Chr15:70512774-70516703 (-)
LP/J MGP_LPJ_G0021837
 protein coding gene Chr15:74584585-74588514 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021770
 protein coding gene Chr15:85192151-85196080 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022362
 protein coding gene Chr15:74095770-74099699 (-)
PWK/PhJ MGP_PWKPhJ_G0020934
 protein coding gene Chr15:71570503-71575306 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020775
 protein coding gene Chr15:73984226-73988141 (-)
WSB/EiJ MGP_WSBEiJ_G0021245
 protein coding gene Chr15:74107728-74111657 (-)



Homology
more
  • Human Ortholog
    SLURP2, secreted LY6/PLAUR domain containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLURP2, secreted LY6/PLAUR domain containing 2
  • Synonyms
    SLURP-2
  • Links
    NCBI Gene ID: 432355
    neXtProt AC: NX_P0DP57
    UniProt: P0DP57

  • Chr Location
    8q24.3; chr8:142764338-142769828 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Slurp2 mouse models

Human Disease Mouse Models
      
IDs
 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout results in hyperkeratosis of the paw skin, slow postnatal weight gain and reduced body fat mass.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69462 NCBI Gene Model | MGI Sequence Detail 3849 C57BL/6J ±  kb
    transcript NM_001081961 RefSeq | MGI Sequence Detail 464 Not Specified  
    polypeptide P0DP59 UniProt | EBI | MGI Sequence Detail 97 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 1
    References
    more
    • Summaries
      All 51
      Diseases 2
      Gene Ontology 6
      Phenotypes 31
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory