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Chst8
Gene Detail
 Symbol
Name
ID
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
MGI:1916197
Synonyms 1500011J21Rik, GalNAc4ST-1
Feature Type protein coding gene
Genetic Map
Chromosome 7
20.53 cM, cytoband B3-B5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:34674468-34812711 bp, - strand
From VEGA annotation of GRCm38

  138244 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41483  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Chst8

Human
homologs
Human Homolog CHST8, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
NCBI Gene ID 64377
neXtProt AC  NX_Q9H2A9
Human Synonyms  GalNAc4ST, GALNAC4ST1
Human Chr (Location)  19q13.1; chr19:33621955-33773509 (+)  GRCh38
Alleles
and
phenotypes
All alleles(69) : Gene trapped(65) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Male mice homozygous for a null allele show higher luteinizing hormone and testosterone levels, early sexual maturation and enlarged seminal vesicles; females show higher LH, estrogen and progesterone levels, early sexual maturation, enlarged uteri, a prolonged estrous cycle and increased fecundity.
 
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process carbohydrate biosynthetic process, carbohydrate metabolic process, ...
Component Golgi apparatus, integral component of membrane, ...
Function 1-hydroxypyrene sulfotransferase activity, 1-phenanthrol sulfotransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (98)    Tissues (23)    Images (21)
Theiler Stages: 23
Assay TypeResults
RNA in situ 98
cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000029096 (Evidence)
Ensembl Gene ModelENSMUSG00000060402 (Evidence)
Entrez Gene68947 (Evidence)
UniGene29380
DFCITC1584621, TC1613564
DoTSDT.91367905, DT.91593089
NIA Mouse Gene IndexU028431, U325272
EC2.8.2.-
Consensus CDS ProjectCCDS21142.1
International Mouse Knockout Project StatusChst8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029096 VEGA Gene Model | MGI Sequence Detail 138244 C57BL/6J ±  kb
transcript OTTMUST00000072157 VEGA | MGI Sequence Detail 2372 Not Applicable 
polypeptide OTTMUSP00000037073 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(12) UniProt(2)
Polymorphisms SNPs within 2kb(1785 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018011 Carbohydrate sulfotransferase-related
InterPro IPR005331 Sulfotransferase
Protein Ontology PR:000005481 carbohydrate sulfotransferase 8
References (Earliest) J:66120 Xia G, et al., Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. J Biol Chem. 2000 Dec 8;275(49):38402-9
(Latest) J:182757 Wilson DG, et al., Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25
All references(40)
Other
accession IDs
MGI:2141936

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory