About   Help   FAQ
Chst8
Gene Detail
Symbol

Name
ID
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
MGI:1916197
Synonyms
1500011J21Rik, GalNAc4ST-1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
20.53 cM, cytoband B3-B5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:34674468-34812711 bp, - strand
From VEGA annotation of GRCm38

  138244 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41483  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CHST8
Gene Tree: Chst8

Human
homologs
CHST8, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 64377
neXtProt AC: NX_Q9H2A9

Human Synonyms: GalNAc4ST, GALNAC4ST1, PSS3

Human Chr (Location): 19q13.1; chr19:33621955-33773509 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CHST8

Mutations,
alleles, and
phenotypes
All mutations/alleles(69) : Gene trapped(65) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Male mice homozygous for a null allele show higher luteinizing hormone and testosterone levels, early sexual maturation and enlarged seminal vesicles; females show higher LH, estrogen and progesterone levels, early sexual maturation, enlarged uteri, a prolonged estrous cycle and increased fecundity.
 
Interactions
Chst8 interacts with 208 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (98)    Tissues (23)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase chst8    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000029096 (Evidence)
Ensembl Gene Model ENSMUSG00000060402 (Evidence)
Entrez Gene 68947 (Evidence)
UniGene 29380
DFCI TC1584621, TC1613564
DoTS DT.91593089, DT.91367905
NIA Mouse Gene Index U028431, U325272
EC 2.8.2.-
Consensus CDS Project CCDS21142.1
International Mouse Phenotyping Consortium Status Chst8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029096 VEGA Gene Model | MGI Sequence Detail 138244 C57BL/6J ±  kb
transcript OTTMUST00000072157 VEGA | MGI Sequence Detail 2372 Not Applicable 
polypeptide OTTMUSP00000037073 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10) UniProt(2)
Polymorphisms
SNPs within 2kb(1785 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018011 Carbohydrate sulfotransferase-related
InterPro IPR005331 Sulfotransferase
Protein Ontology PR:000005481 carbohydrate sulfotransferase 8
References
(Earliest) J:66120 Xia G, et al., Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. J Biol Chem. 2000 Dec 8;275(49):38402-9
(Latest) J:219340 Molyneaux BJ, et al., DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21;85(2):275-88
All references(39)
Other
accession IDs
MGI:2141936

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/20/2015
MGI 5.22
The Jackson Laboratory