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Chst8
Gene Detail
Symbol

Name
ID
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
MGI:1916197
Synonyms
1500011J21Rik, GalNAc4ST-1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
20.53 cM, cytoband B3-B5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:34674468-34812711 bp, - strand
From VEGA annotation of GRCm38

  138244 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41483  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Chst8

Human
homologs
Human Homolog CHST8, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
NCBI Gene ID 64377
neXtProt AC  NX_Q9H2A9
Human Synonyms  GalNAc4ST, GALNAC4ST1
Human Chr (Location)  19q13.1; chr19:33621955-33773509 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(69) : Gene trapped(65) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Male mice homozygous for a null allele show higher luteinizing hormone and testosterone levels, early sexual maturation and enlarged seminal vesicles; females show higher LH, estrogen and progesterone levels, early sexual maturation, enlarged uteri, a prolonged estrous cycle and increased fecundity.
 
Interactions
Chst8 interacts with 209 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (98)    Tissues (23)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000029096 (Evidence)
Ensembl Gene ModelENSMUSG00000060402 (Evidence)
Entrez Gene68947 (Evidence)
UniGene29380
DFCITC1584621, TC1613564
DoTSDT.91367905, DT.91593089
NIA Mouse Gene IndexU028431, U325272
EC2.8.2.-
Consensus CDS ProjectCCDS21142.1
International Mouse Knockout Project StatusChst8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029096 VEGA Gene Model | MGI Sequence Detail 138244 C57BL/6J ±  kb
transcript OTTMUST00000072157 VEGA | MGI Sequence Detail 2372 Not Applicable 
polypeptide OTTMUSP00000037073 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(12) UniProt(3)
Polymorphisms
SNPs within 2kb(1785 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018011 Carbohydrate sulfotransferase-related
InterPro IPR005331 Sulfotransferase
Protein Ontology PR:000005481 carbohydrate sulfotransferase 8
References
(Earliest) J:66120 Xia G, et al., Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. J Biol Chem. 2000 Dec 8;275(49):38402-9
(Latest) J:182757 Wilson DG, et al., Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25
All references(40)
Other
accession IDs
MGI:2141936

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory