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Ppfia4 Gene Detail
Summary
  • Symbol
    Ppfia4
  • Name
    protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
  • Synonyms
    1110008G13Rik, Gm3812, Liprin-alpha4, Liprin-alpha4a, Liprin-alpha4b, LOC100042382
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915757
    NCBI Gene: 68507
  • Gene Overview
    MyGene.info: PPFIA4
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:134296783-134332928 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 58.18 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    401 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915757
protein coding gene Chr1:134296783-134344757 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016503
protein coding gene Chr1:137944846-138001099 (-)
A/J MGP_AJ_G0016486
protein coding gene Chr1:132759578-132807756 (-)
AKR/J MGP_AKRJ_G0016451
protein coding gene Chr1:136718722-136768561 (-)
BALB/cJ MGP_BALBcJ_G0016446
protein coding gene Chr1:133095594-133142949 (-)
C3H/HeJ MGP_C3HHeJ_G0016272
protein coding gene Chr1:136819518-136871186 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016907
protein coding gene Chr1:142976988-143034150 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014618
protein coding gene Chr1:125901560-125938241 (-)
CAST/EiJ MGP_CASTEiJ_G0015852
protein coding gene Chr1:135867286-135919977 (-)
CBA/J MGP_CBAJ_G0016245
protein coding gene Chr1:147934963-147985305 (-)
DBA/2J MGP_DBA2J_G0016351
protein coding gene Chr1:131770971-131819322 (-)
FVB/NJ MGP_FVBNJ_G0016350
protein coding gene Chr1:130397602-130436539 (-)
LP/J MGP_LPJ_G0016422
protein coding gene Chr1:139225352-139278107 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016375
protein coding gene Chr1:153629679-153680475 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016943
protein coding gene Chr1:136448735-136485807 (-)
PWK/PhJ MGP_PWKPhJ_G0015638
protein coding gene Chr1:130788805-130839497 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015425
protein coding gene Chr1:135416279-135465480 (-)
WSB/EiJ MGP_WSBEiJ_G0015915
protein coding gene Chr1:136481412-136520106 (-)



Homology
more
  • Human Ortholog
    PPFIA4, PTPRF interacting protein alpha 4
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PPFIA4, PTPRF interacting protein alpha 4
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 8497
    neXtProt AC: NX_O75335
    UniProt: O75335

  • Chr Location
    1q32.1; chr1:203026491-203078736 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026458 Ensembl Gene Model | MGI Sequence Detail 36146 C57BL/6J ±  kb
transcript ENSMUST00000168515 Ensembl | MGI Sequence Detail 6067 Not Applicable  
polypeptide ENSMUSP00000128314 Ensembl | MGI Sequence Detail 1187 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138244, MGI:2138361, MGI:2138702, MGI:3823247
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:201692 Wentzel C, et al., mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking. Neuron. 2013 Jun 19;78(6):1012-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory