About   Help   FAQ
Rnaseh2c
Gene Detail
 Symbol
Name
ID
Rnaseh2c
ribonuclease H2, subunit C
MGI:1915459
Synonyms 1500026D16Rik
Feature Type protein coding gene
Genetic Map
Chromosome 19
4.34 cM, cytoband A
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:5601873-5603439 bp, + strand
From VEGA annotation of GRCm38

  1567 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32666  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Rnaseh2c

Human
homologs
Human Homolog RNASEH2C, ribonuclease H2, subunit C
NCBI Gene ID 84153
neXtProt AC  NX_Q8TDP1
Human Synonyms  AGS3, AYP1
Human Chr (Location)  11q13.1; chr11:65717673-65720938 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human RNASEH2C
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Interactions
Rnaseh2c interacts with 70 markers (Mir17, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process RNA catabolic process
Component nucleus, ribonuclease H2 complex
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (5)    Images (6)
Theiler Stages: 24, 26, 28
Assay TypeResults
RNA in situ 10
cDNA source data(64)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(65) cDNA(65)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000020425 (Evidence)
Ensembl Gene ModelENSMUSG00000024925 (Evidence)
Entrez Gene68209 (Evidence)
UniGene246200
DFCITC1578262, TC1615329, TC1745409
NIA Mouse Gene IndexU038713
PDB3KIO, 3P5J
Consensus CDS ProjectCCDS29471.1
International Mouse Knockout Project StatusRnaseh2c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020425 VEGA Gene Model | MGI Sequence Detail 1567 C57BL/6J ±  kb
transcript OTTMUST00000048488 VEGA | MGI Sequence Detail 1126 Not Applicable 
polypeptide OTTMUSP00000022240 VEGA | MGI Sequence Detail 166 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013924 Ribonuclease H2, subunit C
Protein Ontology PR:000014056 ribonuclease H2 subunit C
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:198961 Ghodgaonkar MM, et al., Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair. Mol Cell. 2013 May 9;50(3):323-32
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/23/2014
MGI 5.19
The Jackson Laboratory